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99% EP Standard Oxaliplatin CAS:61825-94-3 for Anti Cancer API

Name: 99% EP Standard Oxaliplatin CAS:61825-94-3 for Anti Cancer API
Brand: HyperChem
SKU: pr2610152413
Price: 35 USD
Availability: InStock

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Unit Price:

$35-45/G FOB

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CAS No.:

61825-94-3

Grade:

Pharmaceutical Grade

Content:

99.9%

Port:

Shanghai

Brand:

HyperChem

Packaging:

1kg/bag, 5kg/bag, 25kg/Drum

Sample Available:

Yes

Price valid (until):

2028-11-30

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

10 days

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information
Inquiry History

Description

Name	Oxaliplatin
CAS number	61825-94-3
Synonym	oxaliplatin cis-oxalato-trans-l-1,2-diaminocyclohexaneplatinum(II) CAS-61825-94-3 Oxaliplatin [USAN:INN:BAN] NCGC00167798-01
Description	Product Overview Oxaliplatin is a third-generation platinum-containing antineoplastic agent, chemically described as [(1R,2R)-1,2-cyclohexanediamine-N,N ′ ][ethanedioato(2-)-O,O ′ ]platinum(II). It is supplied as an active pharmaceutical ingredient (API) for the manufacture of finished oncology dosage forms, and is also available as finished pharmaceutical preparations depending on the buyer's registration status. Since its introduction, oxaliplatin has become one of the most widely used cytotoxic agents worldwide and is included in standard treatment protocols and national essential medicine lists in many countries. This product is intended strictly for licensed pharmaceutical manufacturers, distributors, hospitals and research institutions. Physicochemical Properties CAS Number: 61825-94-3 Molecular Formula: C₈H ₁₄ N ₂ O ₄ Pt Molecular Weight: 397.29 g/mol Appearance: White to off-white crystalline powder Solubility: Slightly soluble in water, very slightly soluble in methanol, practically insoluble in anhydrous ethanol Optical rotation: Positive specific rotation, consistent with the (1R,2R)-trans configuration Stability: Sensitive to light, moisture and elevated temperature; decomposes on heating rather than showing a sharp melting point Typical specification covers appearance, identification (IR/HPLC), assay (commonly 98.0%–102.0% on dried basis), related substances, platinum content, loss on drying, residual solvents (ICH Q3C), heavy metals and bacterial endotoxins. Each batch is released with a Certificate of Analysis; DMF/CEP/technical package support and GMP documentation are available on request. Mechanism of Action Oxaliplatin is a prodrug that requires intracellular activation. Through displacement and aquation reactions, the oxalate leaving group is removed to generate reactive diaminocyclohexane (DACH)-platinum species. These species bind preferentially to the N7 position of guanine and form intra-strand and, to a lesser extent, inter-strand DNA crosslinks, mainly guanine–guanine and adenine–guanine adducts. The resulting distortion of the DNA double helix blocks DNA replication and transcription, induces S-phase and G2/M cell-cycle arrest, and ultimately triggers apoptosis. A key feature that distinguishes oxaliplatin from cisplatin and carboplatin is its bulky, hydrophobic DACH carrier ligand. The DACH ring protrudes into the DNA major groove and is poorly recognised by the mismatch-repair (MMR) complex and by certain damage-recognition proteins. As a result, cytotoxic activity is largely independent of MMR status, replicative bypass is prevented, and there is a lack of complete cross-resistance with cisplatin and carboplatin. Oxaliplatin therefore retains activity in tumour models resistant to earlier platinum agents. Cellular uptake is additionally facilitated by organic cation transporters (OCT1/OCT2), which are highly expressed in colorectal cancer cells. Usage and Clinical Applications Oxaliplatin is a prescription cytotoxic agent used by qualified oncologists in the management of solid tumours. Its principal approved indications are: (1) adjuvant treatment of stage III colon cancer following complete resection of the primary tumour, and (2) treatment of advanced or metastatic colorectal cancer. It is also widely used in established protocols for gastric, oesophageal, pancreatic, biliary tract and hepatocellular malignancies, in both adjuvant and palliative settings, according to local labelling and clinical guidelines. Treatment decisions, patient selection, dose individualisation and monitoring are entirely the responsibility of the treating physician; the product must be prescribed, dispensed and used under professional supervision. Combination Therapy Oxaliplatin is rarely used as a single agent; its greatest value lies in combination regimens: Folinic acid/leucovorin + 5-fluorouracil + oxaliplatin), including FOLFOX4 and mFOLFOX6 variants — the reference adjuvant and first-line palliative backbone in colorectal cancer. Capecitabine + oxaliplatin), an oral-fluoropyrimidine alternative with comparable efficacy and a convenient schedule. Combinations with targeted agents such as bevacizumab, cetuximab or panitumumab, selected by biomarker status and clinical judgement. Sequential use with irinotecan-based regimens (e.g., FOLFIRI) in the continuum of metastatic colorectal cancer care. Adverse Reactions and Safety Profile The most characteristic toxicity is peripheral sensory neuropathy, which presents in two forms. The acute form appears within hours to days of dosing as cold-triggered paraesthesia, dysaesthesia or numbness of the hands, feet and perioral region, sometimes with pharyngolaryngeal discomfort, jaw spasm or muscle cramps; it is transient and generally reversible. The chronic form is cumulative and dose-limiting, presenting as persistent distal sensory loss, tingling and functional impairment that may affect daily activities; it typically emerges after several treatment cycles and may improve slowly after discontinuation, though it can persist in some patients. Other commonly reported effects include gastrointestinal reactions (nausea, vomiting, diarrhoea, mucositis, constipation, anorexia), myelosuppression (neutropenia, thrombocytopenia, anaemia, usually mild to moderate), fatigue, fever, and hypersensitivity reactions ranging from rash and urticaria to bronchospasm and anaphylaxis. Hepatic effects such as transaminase elevation and sinusoidal vascular injury have been described. Compared with cisplatin, oxaliplatin causes markedly less nephrotoxicity and ototoxicity, although renal function should still be monitored. Rare events include immune-mediated haemolytic anaemia, thrombotic microangiopathy, interstitial lung disease and posterior reversible encephalopathy syndrome. Regular monitoring of full blood count, renal and hepatic function and neurological status is recommended throughout therapy. Oxaliplatin is contraindicated in patients with known hypersensitivity to platinum compounds and should not be used during pregnancy or breastfeeding; effective contraception is advised during treatment. Handling, Storage and Packaging Store in a tightly closed, light-resistant container in a cool, dry place; refrigerated storage (2–8 °C) is commonly specified for long-term retention, with protection from moisture. As a cytotoxic compound, it must be handled only by trained personnel using appropriate containment, personal protective equipment and waste disposal procedures in accordance with local regulations and the Safety Data Sheet. Standard pack sizes include 1 g, 5 g, 10 g, 25 g and 100 g in aluminium foil bags or HDPE bottles, with customised pack sizes, labelling and documentation available. Compliance Statement Prescription-only medicine. For licensed pharmaceutical manufacturers, healthcare institutions and research use only. Not for sale to or use by individual consumers, and not for food, cosmetic or veterinary applications. Buyers are responsible for holding all import, distribution and pharmaceutical licences required in their jurisdiction.
Structure
Molecular Formula	C ₈ H ₁₄ N ₂ O ₄ Pt
Molecular Weight	397.29 g/mol
Appearance	White or almost white crystalline powder
Quality Standard	USP EP
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Dry, dark and at 2~8 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Fiber drum
Origin	China

Product Image

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FAQ

Q1. What is the Hyper chem payment term?
T/T advance
LC at sight
DP at sight
Trade assurance
Money gram

Q2. What is Hyper chem shipment policy?
Our policy is to strive for the quickest shipment time possible, with ready stock sample shipment typically going out the same day that your order was placed. Your satisfaction is very important to us.
For non-ready stock, please contact the Hyper Chem sales team to negotiate.

Q3. What hyper chem will provide after shipment?
For sample orders:
After shipment is done, an timely email including:

Track details (Fedex /TNT/DHL/EMS Track number)

Package photo

COA, MSDS, etc

Dispatch date & Estimated arriving time

Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided
in scan-copy and original, to help customers complete the customs clearance process.

Q4. What is Hyper Chem shipment term?

By Express
DHL  FedEx  TNT  EMS
Fast:5 days around
High cost, door to door service

By Air
Suitable for more than 50kg
Fast :3-7 days Hight cost, port to port, professional broker needed

By Sea
Suitable for more than 500kg
Slow:7-45 days, Low cost, port to port, professional broker needed
We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. Does hyper chem provide a shipment return policy?
Yes, we have.
Return Policy: At Hyper chem, your satisfaction is guaranteed. If you are dissatisfied for any reason with a product, please send back the unused portion along with your packing slip and a brief note on why you were dissatisfied within 45 days of purchase for a full refund to:

Q6. What is hyper chem After-sales service
•Documents support: COA ,MSDS, MOA ,MS Report,HNMR Report,SDS,DMF
• Customer Support: Shipment clearance support, quality issue support
• Automated Customer Service: Our worldwide customers enjoy immediate 24/7 access to the HYPER CHEM support team from any location, at any time.

Company profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.

ECHEMI Editorial Reference

Oxaliplatin is a DNA synthesis inhibitor. It causes DNA crosslinking damage, prevents DNA replication and transcription and causes cell death.

Certificates

Basic Info

Product Name:

Oxaliplatin

Other Name:

Platinum,[(1R,2R)-1,2-cyclohexanediamine-κN1,κN2][ethanedioato(2-)-κO1,κO2]-,(SP-4-2)-;Platinum,(1,2-cyclohexanediamine-N,N′)[ethanedioato(2-)-O,O′]-,[SP-4-2-(1R-trans)]-;Platinum,[(1R,2R)-1,2-cyclohexanediamine-κN,κN′][ethanedioato(2-)-κO1,κO2]-,(SP-4-2)-;1,2-Cyclohexanediamine,platinum complex,(1R-trans)-;(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-κN1,κN2][ethanedioato(2-)-κO1,κO2]platinum;NSC 266046;Oxalatoplatinum;Oxalatoplatin;l-OHP;Oxaliplatin;RP 54780;Platinum,(1,2-cyclohexanediamine-κN,κN′)[ethanedioato(2-)-κO1,κO2]-,[SP-4-2-(1R-trans)]-;Oxalato[trans-(-)-1,2-cyclohexanediamine]platinum(II);Oxalato(trans-l-1,2-cyclohexanediamine)platinum(II);Eloxatin;Dacplat;trans-L-Diaminocyclohexane oxalatoplatinum;Elplat;Lipoxal

CAS No.:

61825-94-3

Molecular Formula:

C8H14N2O4Pt

InChIKeys:

InChIKey=ZROHGHOFXNOHSO-BNTLRKBRSA-L

Molecular Weight:

397.28600

Exact Mass:

397.06000

HScode:

28439000

Categories:

Antineoplastic Agents

Characteristics

PSA:

104.64000

XLogP3:

0.61450

Boiling Point:

193.6ºC at 760 mmHg

Flash Point:

75ºC

Water Solubility:

Slightly soluble in water, very slightly soluble in methanol, practically insoluble in anhydrous ethanol. | soluble in water with heating and/or sonication

Toxicity:

LD50 intraperitoneal in mouse: 19800ug/kg

See More Oxaliplatin Properties 

Hazard Identification

Classification of the substance or mixture

Skin irritation, Category 2

Skin sensitization, Category 1

Eye irritation, Category 2

Specific target organ toxicity â single exposure, Category 3

Carcinogenicity, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H315 Causes skin irritation H317 May cause an allergic skin reaction H319 Causes serious eye irritation H335 May cause respiratory irritation H351 Suspected of causing cancer
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P271 Use only outdoors or in a well-ventilated area. P203 Obtain, read and follow all safety instructions before use.
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P333+P317 If skin irritation or rash occurs: Get medical help. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell. P318 IF exposed or concerned, get medical advice.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Oxaliplatin Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Company Certificates
- Certification Report by Bureau Veritas
About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

11 Inquiries

Country	Product	Purchase Quantity	Date Posted
United Arab Emirates	Oxaliplatin	2.00 KG	Oct 15, 2026
India	oxaliplatin	5 KG	Nov 20, 2025
India	Oxaliplatin	2.00 KG	Jul 1, 2026
India	Oxaliplatin	500 G	Feb 27, 2026
Bangladesh	Oxaliplatin	25 KG	Sep 23, 2025
United Arab Emirates	Oxaliplatin	5.00 KG	Oct 8, 2026
United Arab Emirates	Oxaliplatin	1.00 KG	Aug 26, 2026
India	Oxaliplatin	1.00 KG	Aug 11, 2026
India	oxaliplatin	1 KG	Jan 9, 2026
Japan	Oxaliplatin(GMP+CEP)	100 G	May 10, 2024
Bangladesh	Butyl Acetate	1.00 KG	Nov 11, 2025

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99% EP Standard Oxaliplatin CAS:61825-94-3 for Anti Cancer API

Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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