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L-Proline 147-85-3 Good Grade

Name: L-Proline 147-85-3 Good Grade
Brand: orient
SKU: pr2611031560
Price: 45 USD
Availability: InStock

36 Inquiries

Unit Price:

$45-56/MT FOB

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CAS No.:

147-85-3

Grade:

Industrial Grade

Content:

99%

Port:

Brand:

orient

Packaging:

1KG, 5KG, 25KG

Sample Available:

Yes

Price valid (until):

2028-07-14

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Payment Terms:

100% TT in advance

Average Lead Time:

10 days

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Details
Seller Information
Inquiry History

Description

Product Name:	Dermorphin
Synonyms:	DERMORPHIN ACETATE;L-Tyr-D-Ala-L-Phe-Gly-L-Tyr-L-Pro-L-Ser-NH2;Tyrosyl-alanyl-phenylalanyl-glycyl-tyrosyl-prolyl-serinamide;Dermorphin trifluoroacetate salt;Dermorphin Powder;(2S)-N-[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]-1-[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxamide;Dermorphin HAc;(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenyl-propanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]-N-[(1S)-1-carbamoyl-2-hydro
CAS:	77614-16-5
MF:	C40H50N8O10
MW:	802.87
EINECS:	202-853-6
Product Categories:	77614-16-5
Mol File:	77614-16-5.mol

Dermorphin Chemical Properties

Melting point	157-159 °C
Boiling point	1323.8±65.0 °C(Predicted)
density	1.363±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	Soluble in DMSO
form	powder
pka	9.83±0.15(Predicted)
color	white to off-white
Sequence	H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2
InChIKey	FHZPGIUBXYVUOY-VWGYHWLBSA-N
SMILES	C(N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N)(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](C)NC(=O)[C@@H](N)CC1C=CC(O)=CC=1)CC1C=CC=CC=1)CC1C=CC(O)=CC=1

Safety Information

WGK Germany

MSDS Information

Dermorphin Usage And Synthesis

Structure	Dermorphin does not contain the common N-terminal sequence for the traditional endogenous peptides (Tyr–Gly–Gly–Phe), and its sequence is completely different from those of the endomorphins, which were identified as endogenous μ- peptides that also do not contain the common sequence. Interestingly, DM contains D-alanine (a D-isomer amino acid) in its sequence. The primary structure of dermorphin is YDAFGYPS-NH2.
Description	Dermorphin was first isolated from the skin of the skin of South American frogs of the genus Phyllomedusa. It is a high potency natural opiate peptide that binds selectively to mu- receptors.
Uses	A mu- receptor agonist
Definition	ChEBI: Dermorphin is an oligopeptide.
Side effects	Like μ-opiate agonists, dermorphins produce antinociception and also catalepsy, respiratory depression, constipation, tolerance, and dependence, although at a lower degree than does[1].
in vitro	Dermorphin, a peptide isolated from the skin of Phyllomedusa frogs and the peptide receptor (NOP) component by the endogenous agonist nociceptin/orphanin FQ (N/OFQ). In displacement binding studies at CHOhMu, Dermorphin and DeNo displac the binding of [3H]-DPN in a concentration dependent and saturable manner. Dermorphin displays an affinity of 7.17, while N/OFQ fails to displace [3H]-DPN at the Delta receptor. Dermorphin and DeNo stimulate the binding of GTPγ[35S] in a concentration dependent and saturable manner at the Mu receptor.
References	[1] Negri, L. P. Melchiorri and R. Lattanzi. “ and Bv8 Peptides.”Handbook of Biologically Active Peptides (Second Edition) 2013:376-383.

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

Q4:What if there are quality issues？

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

ECHEMI Editorial Reference

L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

Basic Info

Product Name:

L-Proline

Other Name:

L-Proline;Proline,L-;Proline;L-(-)-Proline;2-Pyrrolidinecarboxylic acid,(S)-;(S)-(-)-Proline;2-Pyrrolidinecarboxylic acid;(-)-Proline;(S)-Proline;(S)-2-Pyrrolidinecarboxylic acid;(-)-2-Pyrrolidinecarboxylic acid;L-Pyrrolidine-2-carboxylic acid;L-α-Pyrrolidinecarboxylic acid;Carboxypyrrolidine;NSC 46703;(S)-2-Carboxypyrrolidine;(2S)-Pyrrolidine-2-carboxylic acid;21: PN: WO2021055880 SEQID: 22 claimed protein;7005-20-1;95650-41-2;1150316-19-0

CAS No.:

147-85-3

Molecular Formula:

C5H9NO2

InChIKeys:

InChIKey=ONIBWKKTOPOVIA-BYPYZUCNSA-N

Molecular Weight:

115.13000

Exact Mass:

115.13

EC Number:

205-702-2

HScode:

2933990090

Categories:

Inhibitor Drugs

Characteristics

PSA:

49.33000

XLogP3:

-2.5

Appearance:

Solid

Density:

1.4063 g/cm³ @ Temp: 45.00 °C

Melting Point:

220-222 °C (decomp)

Boiling Point:

252.2ºC at 760 mmHg

Flash Point:

106.3ºC

Refractive Index:

-85 ° (C=4, H2O)

Water Solubility:

H2O: soluble

Storage Conditions:

Store at RT.

Vapor Pressure:

0.00615mmHg at 25°C

Specific rotation:

SPECIFIC OPTICAL ROTATION: -80.9 DEG @ 20 °C/D (WATER, 1%); SADTLER REF NUMBER: 1905 (IR, PRISM)

Odor:

Odorless

Taste:

Sweet

See More L-Proline Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Non Combustible Solids.

See More L-Proline Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10 days

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

36 Inquiries

Country	Product	Purchase Quantity	Date Posted
New Zealand	L-Proline	1 KG	Nov 1, 2026
India	L-Proline	1000.00 KG	May 20, 2026
United States	L-Proline	1000 KG	Apr 22, 2026
Greece	PROLINE (Pro,P)	700.00 KG	Sep 24, 2025
India	L Proline	500.00 KG	Jun 5, 2025
Germany	Potassium Sorbate	50.00 KG	May 8, 2025
Germany	L-carnitine	25.00 KG	May 8, 2025
India	L-Proline	1 MT	Apr 23, 2025
Egypt	L-prolin	8000 KG	Apr 10, 2025
India	L- Proline	5 KG	Apr 9, 2025
India	L-Proline	25.00 KG	Mar 31, 2025
India	Sodium Hydroxide	100.00 KG	Feb 13, 2025
India	L-Tyrosine	25.00 KG	Feb 13, 2025
India	L-Tryptophan powder	25.00 KG	Feb 13, 2025
India	L-Proline	2.00 MT	Feb 9, 2025
Israel	2-Butylaminoethanol	5 KG	Feb 5, 2025
Israel	L-Proline	5 KG	Feb 5, 2025
Israel	1-Ethylimidazole	50 KG	Feb 5, 2025
India	L Proline	1 TON	Nov 6, 2024
India	L -Proline	1000 KG	Aug 14, 2024

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L-Proline 147-85-3 Good Grade

Product Details

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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