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Anti-CD3

Anti-CD3 structure

CAS No:
140608-64-6
Chemical Name:
Anti-CD3
Synonyms:
Muromonab CD3;OKT 3;Orthoclone OKT 3;Muromonab;Anti-CD3;907157-77-1
Categories:
Active Pharmaceutical Ingredients > Drugs Influencing Immune Function

Description

Muromonab-CD3 is a murine monoclonal antibody to the T3 antigen of human T-cells, which blocks their killing ability. It is useful in the treatment of acute allograft rejection in renal transplant patients.Muromonab-CD3 (murine, Orthoclone-OKT3) is an unmodified mouse immunoglobulin, an IgG2a, monoclonal. It binds a glycoprotein on the surface of mature T lymphocytes. Mature T cells have, as part of the signal transduction machinery of the T-cell receptor complex, a set of three glycoproteins

Anti-CD3 Basic Attributes

Molecular Weight：

0.00000

Characteristics

PSA：

0.00000

XLogP3：

0.00000

Anti-CD3 Use and Manufacturing

Monoclonal antibody (immunosuppressant).Muromonab-(CD3) alters the cell-mediated immune response by binding to the CD3 (cluster of differentiation antigen, T3) glycoprotein on T lymphocytes. It is used for the prevention of acute allograft rejection in kidney and hepatic transplants and as prophylaxis in cardiac transplantation. It is also used to deplete T cells in marrow from donors before bone marrow transplantation.

Recommended Suppliers of Anti-CD3

Wuhan Biolab-reagent Biotechnology Co., LTD Contact Supplier

CN
1 YR

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Trader Supplier of Antibody,Recombinant Protein,ELISA Kit

Research Grade Muromonab

Unit Price: $1300-1314 /UNIT FOB

CAS No.: 140608-64-6

Grade: Research Grade

Content: 95%

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