2-(Trifluoromethyl)isonicotinic acid
-
2-(Trifluoromethyl)isonicotinic acid
structure -
-
CAS No:
131747-41-6
-
Formula:
C7H4F3NO2
-
Chemical Name:
2-(Trifluoromethyl)isonicotinic acid
-
Synonyms:
2-(Trifluoromethyl)pyridine-4-carboxylic acid, 4-Carboxy-2-(trifluoromethyl)pyridine;2-(TRIFLUOROMETHYL)ISONICOTINIC ACID;2-(Trifluoromethyl)pyridine-4-carBoxylicacid;2-(Trifluoromethyl)isonicotinicacid97%;2-trifluoromethyl-4-pyridinecarboxylic acid;2-(Trifluoromethyl)isonicotinic acid 97%;2-(trifluoroMethyl)pyridin-4-carboxylic acid;4-Pyridinecarboxylicacid, 2-(trifluoroMethyl)-
- Categories:
-
CAS No:
Characteristics
50.2
1.3
Off-white Solid
1.484±0.06 g/cm3(Predicted)
217-223℃
338.9±42.0 °C(Predicted)
158.8±27.9 °C
1.475
Slightly soluble in water.
3.71E-05mmHg at 25°C
Safety Information
NONH for all modes of transport
3
22-36/37/38
26-36/37/39
Xn
P305 + P351 + P338
H302-H315-H319
|Warning|H302 (97.67%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P280, P301+P312, P302+P352, P305+P351+P338, P321, P330, P332+P313, P337+P313, P362, and P501|Aggregated GHS information provided by 43 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
2-(Trifluoromethyl)isonicotinic acid Use and Manufacturing
Preparation of 2-Trifluoromethyl-isonicotinic acid from 4-Chloro-2-trifluoromethyl pyridine A mixture of 182 mg (1.0 mmol) 4-Chloro-2-trifluoromethyl pyridine, 18.0 mg PdClPreparation of 2-Trifluoromethyl-isonicotinic acid from 2-(Trifluoromethyl)pyridine- 4-carbonitrile A mixture of 172 mg (1.0 mmol) 2-(trifluoromethyl)pyridine-4-carbonitrile in 0.86 ml ethanol was treated with , 0.20 g (5.0 mmol) sodium hydroxide. The mixture was refluxed for 1.5 hours, cooled to r.t. and the yellow suspension was cooled to r.t., 3.0 ml water and 0.65 ml hydrochloric acid was added. The suspension was cooled to 0-5°C form 30 min., filtered and washed with 2.0 ml water. The beige crystals were dried at 40°C/15mbar/2hour to obtain 0.15 g 2-trifluoromethyl-isonicotinic acid. GC-EI-MS: M 191
Storage temperature 2-8℃
Computed Properties
Molecular Weight:191.11
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:191.01941286
Monoisotopic Mass:191.01941286
Topological Polar Surface Area:50.2
Heavy Atom Count:13
Complexity:204
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 2-(Trifluoromethyl)isonicotinic acid
-
![China]()
CN
4 YRS
Business licensedTrader Supplier of Fluorine containing fine chemicals PharmaceuticalInquiryCAS No.: 131747-41-6Content: 99%
Learn More Other Chemicals
-
3,5-DIBROMO-2-[[[(3,5-DINITROBENZOYL)AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID
535965-38-9
-
3,5-DIBROMO-2-[[[[(2-CHLOROPHENOXY)ACETYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID
532386-89-3
-
3,5-DIBROMO-2-[[[(4-METHYL-3-NITROBENZOYL)AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID
532943-48-9
-
3,5-DIBROMO-2-[[[[3-(2-FURANYL)-1-OXO-2-PROPENYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Formula
586392-09-8
-
3,5-DIBROMO-2-[[[[(2-METHYLPHENOXY)ACETYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Formula
531548-30-8
-
2-(1,8-dibromo-16,18-dioxo-17-azapentacyclo[6.6.5.0~2,7~.0~9,14~.0~15,19~]nonadeca-2,4,6,9,11,13-hexaen-17-yl)benzoic acid Formula
333340-54-8
-
3,5-DIBROMO-2-[[[[3-(PHENOXYMETHYL)BENZOYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Structure
586393-79-5
-
3,5-DIBROMO-2-[[[(4-CHLOROBENZOYL)AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Structure
531530-32-2
-
What is 2-Cyclopentyl-3-(2,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-oxo-4-isoquinolinecarboxylic acid
400073-92-9
-
What is 9-Octadecenoic acid (9Z)-, compd. with N,N-dimethylcyclohexanamine (1:1)
65122-23-8
2-(Trifluoromethyl)isonicotinic acid
SDSRequest for Quotation