6-Methyl-2-pyridinecarbonitrile
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6-Methyl-2-pyridinecarbonitrile
structure -
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CAS No:
1620-75-3
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Formula:
C7H6N2
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Chemical Name:
6-Methyl-2-pyridinecarbonitrile
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Synonyms:
2-Pyridinecarbonitrile,6-methyl-;Picolinonitrile,6-methyl-;6-Methyl-2-pyridinecarbonitrile;2-Cyano-6-methylpyridine;6-Methyl-2-cyanopyridine;2-Methyl-6-cyanopyridine;6-Methylpicolinonitrile;6-Cyano-2-methylpyridine;NSC 26022
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CAS No:
6-Methyl-2-pyridinecarbonitrile Basic Attributes
118.14
118.14
216-588-9
26022
DTXSID60167284
29333990
Characteristics
36.7
0.8
Off-white Solid
1.08±0.1 g/cm3(Predicted)
72-74 °C
0°C
0°C
1.531
0.043mmHg at 25°C
Safety Information
III
6.1
UN 3439 6.1/PG III
3
36/37/38
26-36
Xi
P261-P305 + P351 + P338
H315-H319-H335
|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 40 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
6-Methyl-2-pyridinecarbonitrile Use and Manufacturing
General procedure: Benzonitrile 1a (1 mmol), Na2S*9H2O (1.2 mmol) and DMF (1 mL) were added into a 10 mL bottle. The reactor was placed in a heating magnetic stirrer at 130 C. After 2.5 h, by adding about 3 mL H2O after the reaction to disperse the solid product, the reaction mixture was extracted with EtOAc (3 x 3 mL), and the mixture was purified by column chromatography.
Intermediate in the preparation of selective cyclooxygenase-2 inhibitors and calcium antagonists
Computed Properties
Molecular Weight:118.14
XLogP3:0.8
Hydrogen Bond Acceptor Count:2
Exact Mass:118.053098200
Monoisotopic Mass:118.053098200
Topological Polar Surface Area:36.7
Heavy Atom Count:9
Complexity:133
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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