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Epoprostenol

Epoprostenol structure

CAS No:
35121-78-9
Formula:
C20H32O5
Chemical Name:
Epoprostenol
Synonyms:
(5z,13e)-(15s)-6,9-alpha-epoxy-11-alpha,15-dihydroxyprosta-5,13-dienoate;5Z13E-15S-69-ALPHA-EPOXY-11-ALPHA;PGX(prostaglandin);ProstaglandinI;5-[7-hydroxy-8-(3-hydroxyoct-1-enyl)-4-oxabicyclo[3.3.0]oct-3-ylidene]pentanoic acid;6(9)-Oxy-11,15-dihydroxyprosta-5,13-dienoic acid;PGX;Prostaglandin X
Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Description

It is unstable in aqueous solution and hydrolyzes to form 6-oxo-PGF1α. Its half-life is approximately 14.5 minutes (at 4°C) at 0.165 mol/L of the phosphate ester. Epoprostenol Sodium: C20H31NaO5 [61849-14-7]. A hygroscopic, free-flowing white powder. It can be stored at -30°C and kept dry for 2 months.

ChEBI: Prostaglandin I2 is a prostaglandins I. It has a role as a mouse metabolite. It is a conjugate acid of a prostaglandin I2(1-).

Epoprostenol Basic Attributes

Molecular Weight：

352.47

Exact Mass：

352.47

Characteristics

PSA：

89.82000

XLogP3：

2.07380

Density：

1.221

Boiling Point：

530.2±50.0 °C(Predicted)

Flash Point：

182.1ºC

Refractive Index：

1.611

PKA：

4.70±0.10(Predicted)

Safety Information

hazard class code：

R20/21/22

safety instructions：

S22;S26;S36

Marks：

Epoprostenol Use and Manufacturing

For the treatment of primary pulmonary hypertension.

Inhibitor (platelet). [Names previously used: Prostacyclin, PGI2, Prostagland in I2, Prostaglandin X, PGX].

Material

Potassium tert-butoxide

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Epoprostenol Sodium CAS 35121-78-9

CAS No.: 35121-78-9

Grade: Pharmaceutical Grade

Content: 99%

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