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glycyl-prolyl-glutamic acid

glycyl-prolyl-glutamic acid structure

glycyl-prolyl-glutamic acid 

structure

Description

Gly-Pro-Glu is an oligopeptide.|Neuren Pharmaceuticals was developing Glypromate (glycine-proline glutamate), a naturally occurring small-molecule neuroprotectant derived from IGF-1 which inhibits caspase III dependent apoptosis, for the potential treatment of neurodegenerative diseases by IV infusion. In December 2008, the company discontinued further development of the drug after it failed to show an observable effect.

glycyl-prolyl-glutamic acid Basic Attributes

301.299

301.127

ZYK4RVV5LS

DTXSID80186038

Characteristics

150

-5.1

H2O: >5mg/mL

Store at 0°C

Safety Information

3

Drug Information

Investigated for use/treatment in neurologic disorders.

Gly-Pro-Glu

Computed Properties

Molecular Weight:301.30
XLogP3:-5.1
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:7
Exact Mass:301.12738533
Monoisotopic Mass:301.12738533
Topological Polar Surface Area:150
Heavy Atom Count:21
Complexity:439
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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