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Home > Encyclopedia > N-Acetyl-L-lysine

N-Acetyl-L-lysine

N-Acetyl-L-lysine structure

N-Acetyl-L-lysine 

structure
  • CAS No:

    1946-82-3

  • Formula:

    C8H16N2O3

  • Chemical Name:

    N-Acetyl-L-lysine

  • Synonyms:

    L-Lysine,N2-acetyl-;Lysine,N2-acetyl-,L-;N2-Acetyl-L-lysine;Nα-Acetyl-L-lysine;Nα-Acetyllysine;6-Amino-L-2-acetamidohexanoic acid;N-Acetyl-L-lysine;N2-Acetyllysine;(2S)-6-Amino-2-acetamidohexanoic acid;(2S)-2-Acetamido-6-aminohexanoic acid

  • Categories:

    Biochemical Engineering  >  Amino Acids and Derivatives

Description

Nalpha-Acetyl-L-Lysine is  white to almost white crystalline powder ChEBI: An acetyl-L-lysine where the acetyl group is located at the N2-posiiton.


Solid


N(2)-acetyl-L-lysine is an acetyl-L-lysine where the acetyl group is located at the N(2)-posiiton. It has a role as a human metabolite. It is a tautomer of a N(2)-acetyl-L-lysine zwitterion.

N-Acetyl-L-lysine Basic Attributes

188.22

188.22

217-747-5

7D44E6BN1B

29241990

Characteristics

92.4

-4.4

White Powder

1.1793 (rough estimate)

250 °C (decomp)

323.23°C (rough estimate)

219.0±27.3 °C

1.4500 (estimate)

Soluble in water (miscible), and 80% acetic acid (50 mg/ml--clear colorless solution)).

−20°C

6.45E-09mmHg at 25°C

145.1 Ų [M-H]-

Safety Information

NONH for all modes of transport

3

24/25-22

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Drug Information

N(2)-acetyllysine

N-Acetyl-L-lysine Use and Manufacturing

Nα-Acetyl-L-Lysine is an antibacterial lysine analogue that targets lysine riboswitches. Nα-Acetyl-L-Lysine is used in the metabolomic characterization of ovarian epithelial carcinomas which allows for better therapeutic management of patients. The presence of Nα-Acetyl-L-Lysine and other N-acetylated amino acids in the urine can be used to detect aminoacylase I deficiency.

Computed Properties

Molecular Weight:188.22
XLogP3:-4.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:188.11609238
Monoisotopic Mass:188.11609238
Topological Polar Surface Area:92.4
Heavy Atom Count:13
Complexity:182
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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