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IFENPRODIL HEMITARTRATE

IFENPRODIL HEMITARTRATE structure

IFENPRODIL HEMITARTRATE 

structure
  • CAS No:

    23210-58-4

  • Formula:

    C25H33NO8

  • Chemical Name:

    IFENPRODIL HEMITARTRATE

  • Synonyms:

    2-(4-BENZYLPIPERIDINO)-1-(4-HYDROXYPHENYL)-1-PROPANOL HEMITARTRATE;IFENPRODIL TARTRATE;IFENPRODIL TARTRATE SALT;IFENPRODIL HEMITARTRATE;ALPHA-[4-HYDROXYPHENYL]-BETA-METHYL-4-BENZYL-1-PIPERIDINEETHANOL TARTRATE SALT;a-(4-Hydroxyphenyl)--methyl-4-(phenylmethyl)-1-piperidineethanol (2R,3R)-2,3-Dihydroxybutanedioate;Cerocral;Dilvax

  • Categories:

    Biochemical Engineering  >  Inhibitors

Description

Ifenprodil tartrate is a novel N-methyl-D-aspartate (NMDA) receptor antagonist that selectively inhibits receptors containing the NR2B subunit.


Crystalline Solid


ChEBI: Ifenprodil tartrate is a member of piperidines.


Ifenprodil is a phenylethanolamine, which stimulates blood circulation. It has anticonvulsant and antinociceptive properties. Ifenprodil is used to treat posttraumatic stress disorder, cerebrovascular diseases and peripheral arterial obliterative disease. It blocks G protein-coupled inwardly-rectifying potassium channels (GIRKs) and interacts with α1 adrenergic,N-methyl-D-aspartate and serotonin receptors.

IFENPRODIL HEMITARTRATE Basic Attributes

475.53

800.42479611 g/mol

245-493-5

White

Characteristics

203 Ų

178-180°C

248.7ºC

Soluble in water (15mM, gentle warming)

Refrigerator

Inert atmosphere,2-8°C

Safety Information

NONH for all modes of transport

3

Xn

22-26-36-36/37

Xn

Room temperature

P261-P280-P305 + P351 + P338

20/21/22-36/37/38

IFENPRODIL HEMITARTRATE Use and Manufacturing

Vasodilatator;Adrenergic antagonist


Vasodilator (cerebral and peripheral)


Ifenprodil (+)-tartrate salt has been used:to test the action in a KCl-induced cortical spreading depression (CSD) animalto study its effects on electrophysiological properties and spontaneous spikes in neocortical pyramidal cellsto investigate its therapeutic effects

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