IFENPRODIL HEMITARTRATE
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IFENPRODIL HEMITARTRATE
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CAS No:
23210-58-4
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Formula:
C25H33NO8
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Chemical Name:
IFENPRODIL HEMITARTRATE
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Synonyms:
2-(4-BENZYLPIPERIDINO)-1-(4-HYDROXYPHENYL)-1-PROPANOL HEMITARTRATE;IFENPRODIL TARTRATE;IFENPRODIL TARTRATE SALT;IFENPRODIL HEMITARTRATE;ALPHA-[4-HYDROXYPHENYL]-BETA-METHYL-4-BENZYL-1-PIPERIDINEETHANOL TARTRATE SALT;a-(4-Hydroxyphenyl)--methyl-4-(phenylmethyl)-1-piperidineethanol (2R,3R)-2,3-Dihydroxybutanedioate;Cerocral;Dilvax
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CAS No:
Description
Ifenprodil tartrate is a novel N-methyl-D-aspartate (NMDA) receptor antagonist that selectively inhibits receptors containing the NR2B subunit.
Crystalline Solid
ChEBI: Ifenprodil tartrate is a member of piperidines.
Ifenprodil is a phenylethanolamine, which stimulates blood circulation. It has anticonvulsant and antinociceptive properties. Ifenprodil is used to treat posttraumatic stress disorder, cerebrovascular diseases and peripheral arterial obliterative disease. It blocks G protein-coupled inwardly-rectifying potassium channels (GIRKs) and interacts with α1 adrenergic,N-methyl-D-aspartate and serotonin receptors.
Characteristics
203 Ų
178-180°C
248.7ºC
Soluble in water (15mM, gentle warming)
Refrigerator
Inert atmosphere,2-8°C
Safety Information
NONH for all modes of transport
3
Xn
22-26-36-36/37
Xn
Room temperature
P261-P280-P305 + P351 + P338
20/21/22-36/37/38
IFENPRODIL HEMITARTRATE Use and Manufacturing
Vasodilatator;Adrenergic antagonist
Vasodilator (cerebral and peripheral)
Ifenprodil (+)-tartrate salt has been used:to test the action in a KCl-induced cortical spreading depression (CSD) animalto study its effects on electrophysiological properties and spontaneous spikes in neocortical pyramidal cellsto investigate its therapeutic effects
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