4-Dodecyl-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide
-
4-Dodecyl-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide
structure -
-
CAS No:
1191951-57-1
-
Formula:
C20H31N3O2S2
-
Chemical Name:
4-Dodecyl-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide
-
Synonyms:
Benzenesulfonamide,4-dodecyl-N-1,3,4-thiadiazol-2-yl-;4-Dodecyl-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide;PHT 427;1178893-77-0
- Categories:
-
CAS No:
Description
PHT-247 is an inhibitor of the pleckstrin homology (PH) domain of Akt, and it is also an inhibitor of PDPK1 with Kis of 2.7 µM and 5.2 µM and for Akt and PDPK1, respectively.
4-Dodecyl-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide Basic Attributes
409.62
409.61
543K8ZN6LH
DTXSID90658014
Characteristics
109
7.4
1.162
126-127 °C @ Solvent: Hexane, Ethyl acetate
535.0±43.0 °C(Predicted)
277.4±28.2 °C
1.556
4-Dodecyl-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide Use and Manufacturing
PHT-427 is a dual Akt and PDPK1 inhibitor with Ki of 2.7 μM and 5.2 μM, respectively.
Computed Properties
Molecular Weight:409.6
XLogP3:7.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:14
Exact Mass:409.18576959
Monoisotopic Mass:409.18576959
Topological Polar Surface Area:109
Heavy Atom Count:27
Complexity:474
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 4-Dodecyl-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![United States]()
US
6 YRS
Business licensed Certified factoryManufactory Supplier of Coenzymes,Inhibito,Enzymes,Zymogens,Substrates
Latest News on 4-Dodecyl-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide
- BMS Over $900 Million to Help Develop Potential 'Best-in-class' SHP2 Inhibitors
- AbbVie's blockbuster product for atopic dermatitis, Upadacitinib, has been approved for marketing in the EU and Japan
- Designing peptide inhibitors for possible COVID-19 treatments
- Chinese scientists discover the inhibitors of SARS-CoV-2
Learn More Other Chemicals
-
Dabrafenib
1195765-45-7
-
BOC-VAL-VAL-OH
69209-73-0
-
BMS 303141
943962-47-8
-
(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanamide Formula
60117-17-1
-
(2S)-2-acetamido-6-amino-N-[(2S)-2-amino-3-methylbutanoyl]-N-propylhexanamide Formula
57899-96-4
-
1-(6-methoxy-1,3-benzothiazol-2-yl)-3-phenylurea Formula
26130-02-9
-
L-Tyrosyl-L-phenylalanine Structure
17355-11-2
-
C-REACTIVE PROTEIN FRAGMENT 77-82 Structure
130349-01-8
-
What is Sildenafil
139755-83-2
-
What is Dacomitinib
1110813-31-4
4-Dodecyl-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide
SDSRequest for Quotation