A-674563
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A-674563
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CAS No:
552325-73-2
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Formula:
C22H22N4O
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Chemical Name:
A-674563
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Synonyms:
A-674563;(alphaS)-alpha-[[[5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]benzeneethanamine;A-674563 /A674563;(2S)-1-(5-(3-methyl-1H-indazol-5-yl)pyridin-3-yloxy)-3-phenylpropan-2-amine;(alphaS)-alpha-[[[5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]benzeneethanamineA-674563;A-674563(alphaS)-alpha-[[[5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]benzeneethanamineA-674563 /A674563;(S)-1-(5-(3-Methyl-1H-indazol-5-yl)pyridin-3-yloxy)-3-phenylpropan-2-amine
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CAS No:
A-674563 Use and Manufacturing
A-674563 inhibits Akt1, PKA and CDK2 with Ki of 11 nM, 16 nM and 46 nM, respectively.
Computed Properties
Molecular Weight:358.4
XLogP3:3.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:358.17936134
Monoisotopic Mass:358.17936134
Topological Polar Surface Area:76.8
Heavy Atom Count:27
Complexity:456
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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