 Home > Encyclopedia > CYC-116

CYC-116

CYC-116 structure

CAS No:
693228-63-6
Formula:
C18H20N6OS
Chemical Name:
CYC-116
Synonyms:
CYC-116;4-(2-Amino-4-methyl-5-thiazolyl)-N-[4-(4-morpholinyl)phenyl]- 2-Pyrimidinamine;4-(2-amino-4-methylthiazol-5-yl)-N-(4-morpholinophenyl)pyrimidin-2-amine;CYC-1164-(2-amino-4-methylthiazol-5-yl)-N-(4-morpholinophenyl)pyrimidin-2-amine;4-Methyl-5-(2-((4-morpholinophenyl)amino)-pyrimidin-4-yl)thiazol-2-amine
Categories:
Biochemical Engineering > Inhibitors

Request for Quotation

Description

CYC-116 is a potent aurora A and aurora B inhibitor with Kis of 8 and 9 nM, respectively.

CYC-116 Basic Attributes

Molecular Weight：

368.46

Exact Mass：

368.141937

EC Number：

-0

Characteristics

PSA：

117

XLogP3：

2.6

Density：

1.4±0.1 g/cm3

Flash Point：

346.2±34.3 °C

Refractive Index：

1.689

Drug Information

MeSH Entry Terms：

4-methyl-5-(2-(4-morpholinophenylamino)pyrimidin-4-yl)thiazol-2-amine

CYC-116 Use and Manufacturing

CYC116 is a potent inhibitor of Aurora A/B and VEGFR with Ki of 8.0 nM/9.2 nM and 44 nM, respectively.

Computed Properties

Molecular Weight:368.5
XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:368.14193046
Monoisotopic Mass:368.14193046
Topological Polar Surface Area:117
Heavy Atom Count:26
Complexity:443
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of CYC-116

Dayang Chem (Hangzhou) Co.,Ltd Contact Supplier

CN
3 YRS

Business licensed Certified factory

Manufactory Supplier of N-Diethyl-m-toluamide,6-Methyluracil,Anisole,4-Dimethoxybenzoic acid,CS (lacrimator),Daucosterol,N,N-Formylmorpholine,Epichlorohydrin,Tetramethylguanidine,Dimethicone,3

CYC-116 Manufacturer/High quality/Best price/In stock

CAS No.: 693228-63-6

Content: 98%

Inquiry
Creative Enzymes Contact Supplier

US
6 YRS

Business licensed Certified factory

Manufactory Supplier of Coenzymes,Inhibito,Enzymes,Zymogens,Substrates

CYC-116

CAS No.: 693228-63-6

Content: 95%

Inquiry