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KU57788(NU7441)

KU57788(NU7441) structure

KU57788(NU7441) 

structure
  • CAS No:

    503468-95-9

  • Formula:

    C25H19NO3S

  • Chemical Name:

    KU57788(NU7441)

  • Synonyms:

    KU57788(NU7441);NU 7441;8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one;KU 57788;NU-7441 (KU-57788);4H-1-Benzopyran-4-one, 8-(4-dibenzothienyl)-2-(4-morpholinyl)-;8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-oneNU-7441;8-dibenzothiophen-4-yl-2-morpholin-4-ylchromen-4-one

  • Categories:

    Biochemical Engineering  >  Inhibitors

Description

KU-57788 is a potent and selective inhibitor of DNA-PK with an IC50 of 13 nM, with selectivity over a range of kinases including mTOR, PI 3-K, ATM and ATR.

KU57788(NU7441) Basic Attributes

413.48826

413.108551

-0

Characteristics

67

5.5

1.4±0.1 g/cm3

220-221 °C

646.9°C at 760 mmHg

345.0±31.5 °C

1.732

Store at +4°C

KU57788(NU7441) Use and Manufacturing

A potent and selective DNA-PK inhibitor with an IC50 of 14 nM.

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