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PD184352

PD184352 structure

PD184352 

structure
  • CAS No:

    212631-79-3

  • Formula:

    C17H14ClF2IN2O2

  • Chemical Name:

    PD184352

  • Synonyms:

    PD184352;2-[(2-Chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide;2-(2-CHLORO-4-IODOANILINO)-N-(CYCLOPROPYLMETHOXY)-3,4-DIFLUOROBENZAMIDE;2-[(2-CHLORO-4-IODOPHENYL) AMINO]-N-(CYCLOPROPYLME;Benzamide, 2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluoro-;Ci-1040;CI-1040, PD-184352;3,4-Difluoro-2-(2-chloro-4-iodophenylaMino)-N-cyclopropylMethoxybenzaMide

  • Categories:

    Biochemical Engineering  >  Inhibitors

Description

CI-1040 (PD184352) is an orally active, highly specific, small-molecule inhibitor of MEK with an IC50 of 17 nM for MEK1.

PD184352 Basic Attributes

478.6595364

477.975647

2924299090

Characteristics

50.4

5.6

white to tan

1.7±0.1 g/cm3

166-169°C

1.656

DMSO: ≥30mg/mL

-20°C Freezer

Safety Information

UN 3077 9 / PGIII

3

50/53

60-61

N

P273

H400

PD184352 Use and Manufacturing

An inhibitor of ERK signaling pathway.A MAP kinase inhibitor

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