[6]-Gingerol
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[6]-Gingerol
structure -
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CAS No:
23513-14-6
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Formula:
C17H26O4
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Chemical Name:
[6]-Gingerol
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Synonyms:
3-Decanone,5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-,(5S)-;3-Decanone,5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-,(S)-(+)-;3-Decanone,5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-,(S)-;(5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone;(+)-[6]-Gingerol;[6]-Gingerol;(+)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone;(S)-(+)-[6]Gingerol;(S)-[6]Gingerol;(5S)-[6]-Gingerol;(5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)decan-3-one;3-Decanone 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-,(5S)-;1391-73-7
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CAS No:
Description
[6]-Gingerol is an active compound isolated from Ginger (Zingiber officinale Rosc), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.
Gingerol is a beta-hydroxy ketone that is 5-hydroxydecan-3-one substituted by a 4-hydroxy-3-methoxyphenyl moiety at position 1; believed to inhibit adipogenesis. It is a constituent of fresh ginger. It has a role as an antineoplastic agent and a plant metabolite. It is a beta-hydroxy ketone and a member of guaiacols.
Characteristics
66.8
2.5
light yellow oiliness
1.1±0.1 g/cm3
31 °C
453°C at 760 mmHg
159.0±19.4 °C
1.523
methanol: soluble 1mg/mL, clear, colorless
-20°C
5.39E-09mmHg at 25°C
Safety Information
Ⅲ
UN 2811 6.1 / PGIII
3
22-36/37/38
26-36/37
HE0757000
Xn
P261-P301 + P310-P305 + P351 + P338
H301-H315-H319-H335
|Danger|H301 (58.57%): Toxic if swallowed [Danger Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P310, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 70 companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
[6]-Gingerol Use and Manufacturing
6-gingerol is a biologically active compound with antioxidant activity and is an anti-inflammatory and anti-tumor drug. 6-Gingerol down regulates the release of inflammatory cytokines from macrophages. By inhibiting the activity of p38 MAP kinase and NF-κB, COX-2 expression is inhibited.
Computed Properties
Molecular Weight:294.4
XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:10
Exact Mass:294.18310931
Monoisotopic Mass:294.18310931
Topological Polar Surface Area:66.8
Heavy Atom Count:21
Complexity:293
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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