2-(4-ETHOXYPHENYL)-2-METHYL PROPIONITRILE

The preparation method is to add p-ethoxybenzyl cyanide and the phase transfer catalyst tetrabutylammonium bromide, potassium hydroxide and water into a three-necked flask, add iodomethane dropwise with stirring at 60°C, and continue to add iodomethane after the dropwise addition. Reflux and stir at temperature. After the reflux is slow, the temperature is increased to 80-85°C, reacted for 7h, cooled to room temperature and extracted with benzene, the extract is washed with dilute hydrochloric acid and water, and then the benzene is evaporated to obtain 2-methylp-ethoxy Benzyl cyanide, then mix with tetrabutylammonium bromide and potassium hydroxide aqueous solution, add iodomethane dropwise with stirring at 60℃, continue to stir for 3.5h after dropping, add potassium hydroxide and stir for 5h, then add iodomethane, React for 2h at the same temperature, and process the product according to the above treatment method.

2,2-Dimethyl p-ethoxycyanobenzyl is an intermediate of pyrethroid pyrethroids.

Molecular Weight:189.25
XLogP3:2.8
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:189.115364102
Monoisotopic Mass:189.115364102
Topological Polar Surface Area:33
Heavy Atom Count:14
Complexity:218
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes