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2-(1-Methylethyl)-5-[(1E)-2-phenylethenyl]-1,3-benzenediol

2-(1-Methylethyl)-5-[(1E)-2-phenylethenyl]-1,3-benzenediol structure

CAS No:
79338-84-4
Formula:
C17H18O2
Chemical Name:
2-(1-Methylethyl)-5-[(1E)-2-phenylethenyl]-1,3-benzenediol
Synonyms:
1,3-Benzenediol,2-(1-methylethyl)-5-[(1E)-2-phenylethenyl]-;1,3-Benzenediol,2-(1-methylethyl)-5-(2-phenylethenyl)-,(E)-;2-(1-Methylethyl)-5-[(1E)-2-phenylethenyl]-1,3-benzenediol;3,5-Dihydroxy-4-isopropyl-trans-stilbene;WBI 1001;Tapinarof;(E)-2-Isopropyl-5-styrylbenzene-1,3-diol
Categories:
Active Pharmaceutical Ingredients > Antipyretic Analgesics

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Description

Tapinarof is a natural aryl hydrocarbon receptor (AhR) agonist with an EC50 of 13 nM.

2-(1-Methylethyl)-5-[(1E)-2-phenylethenyl]-1,3-benzenediol Basic Attributes

Molecular Weight：

254.32362

Exact Mass：

254.32

EC Number：

1312995-182-4

Characteristics

PSA：

40.5

XLogP3：

4.39160

Density：

1.158

Drug Function and Efficacy

It can inhibit the activity of lymphocyte protein tyrosine kinase; it has an inhibitory effect on the release of inflammatory cytokines associated with psoriasis, inflammatory cell migration and infiltration, abnormal differentiation and proliferation of keratinocytes, neovascularization and vasodilation.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Benvimod cream
Ingredients	The active ingredient of this product is Benvimod. Chemical name: 5-[(E)-2-phenylvinyl]-2-isopropyl-1,3-benzenediol Molecular formula: C17H18O2 Molecular weight: 254.32 Excipients: hexadecanol, white vaseline, light liquid paraffin, mono- and distearic glyceryl, propylene glycol, polysorbate 80, polyphenylene ethyl ester and purified water.
Indication	Not clear. This trial has not been conducted and there are no reliable references.
Specifications	10g:0.1g(1%)
Manufacturer	Guangdong Zhonghao Pharmaceutical Co., Ltd.

Registered Holders

METROCHEM API PRIVATE LTD

United States
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MAITHRI DRUGS PRIVATE LTD

United States
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MSN ORGANICS PRIVATE LTD

United States
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Recommended Suppliers of 2-(1-Methylethyl)-5-[(1E)-2-phenylethenyl]-1,3-benzenediol

Hubei Meisang Trading Co.,Ltd Contact Supplier

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Factory supply Tapinarof CAS 79338-84-4 Bulk discount available Fast shipping to Australia available

Unit Price: $1 /G FOB

CAS No.: 79338-84-4

Grade: Pharmaceutical Grade

Content: 99%

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DAHAI BIOCHEM LTD Contact Supplier

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1 YR

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Tapinarof

Unit Price: $28 /KG EXW

CAS No.: 79338-84-4

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Guide of 2-(1-Methylethyl)-5-[(1E)-2-phenylethenyl]-1,3-benzenediol

Description
Basic Attributes
Characteristics
Drug Function and Efficacy
Related Drugs
Registered Holders
Recommended Suppliers
Latest News
Learn More Other Chemicals

2-(1-Methylethyl)-5-[(1E)-2-phenylethenyl]-1,3-benzenediol

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