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Enpromate

Enpromate structure

CAS No:
10087-89-5
Formula:
C22H23NO2
Chemical Name:
Enpromate
Synonyms:
Carbamic acid,N-cyclohexyl-,1,1-diphenyl-2-propyn-1-yl ester;Cyclohexanecarbamic acid,1,1-diphenyl-2-propynyl ester;Carbamic acid,cyclohexyl-,1,1-diphenyl-2-propynyl ester;2-Propyn-1-ol,1,1-diphenyl-,cyclohexanecarbamate;2-Propyn-1-ol,1,1-diphenyl-,cyclohexylcarbamate;Enpromate;1,1-Diphenyl-2-propynyl cyclohexylcarbamate;NSC 112682
Categories:
Active Pharmaceutical Ingredients > Antineoplastic Agents

Description

Enpromate is a diarylmethane.|Enpromate is a synthetic acetylenic carbamate, an alkylating agent, with antineoplastic activity.

Enpromate Basic Attributes

Molecular Weight：

333.429

Exact Mass：

333.42

UNII：

HBS2850E4H

NSC Number：

112682

DSSTox ID：

DTXSID30143555

NCI Thesaurus Code：

C83689

HScode：

2924299090

Characteristics

PSA：

38.3

XLogP3：

5.01320

Density：

1.1243 (rough estimate)

Melting Point：

155-157 °C

Boiling Point：

470.38°C (rough estimate)

Flash Point：

242.2ºC

Refractive Index：

1.5614 (estimate)

Toxicity：

LD50 oral in dog: > 250mg/kg

Drug Information

MeSH Entry Terms：

acetylenic carbamate

Enpromate Use and Manufacturing

Antineoplastic.

Computed Properties

Molecular Weight:333.4
XLogP3:5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:333.172878976
Monoisotopic Mass:333.172878976
Topological Polar Surface Area:38.3
Heavy Atom Count:25
Complexity:456
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes