3-AMINO-ISONICOTINIC ACID METHYL ESTER
-
3-AMINO-ISONICOTINIC ACID METHYL ESTER
structure -
-
CAS No:
55279-30-6
-
Formula:
C7H8N2O2
-
Chemical Name:
3-AMINO-ISONICOTINIC ACID METHYL ESTER
-
Synonyms:
METHYL 3-AMINOPYRIDINE-4-CARBOXYLATE;METHYL 3-AMINOISONICOTINATE;AKOS 93360;3-AMINO-ISONICOTINIC ACID METHYL ESTER;3-AMINO-4-PYRIDINECARBOXYLIC ACID METHYL ESTER;3-AMINOPYRIDINE-4-CARBOXYLIC ACID METHYL ESTER;3-Amino-isonicotinic acid methyl ester ,98%;Tpc-py003
- Categories:
-
CAS No:
3-AMINO-ISONICOTINIC ACID METHYL ESTER Basic Attributes
152.15
152.058578
1592732-453-0
DTXSID70363396
2933399090
Safety Information
22-36/38
24/25
Xi,Xn
Irritant
P264, P270, P301+P312, P330, P501
H302
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 40 companies from 2 notifications to the ECHA C&L Inventory.
3-AMINO-ISONICOTINIC ACID METHYL ESTER Use and Manufacturing
(3. 55 g, 25. 7 mmol), H2SO4 (2. 5 ml) and methanol(50 ml) were heated at 80 C for 3 days. The methanol was evaporated, the residue diluted with water(75 ml) and heated to 80 C. Solid sodium carbonate was added until effervescence ceased. The mixture was cooled and extracted with dichloromethane (2 x 100 ml). The combined organic layers were dried overMgS04 and concentrated to give the title compound as a beige solid (2.36 g, 60 percent). 'H NMR (500 MHz, DMSO) 5 8.24 (1H, s), 7.74 (1H, d, J5. 3), 7.46 (1H, d, J5.2), 6.67 (2H, brs), 3.83 (3H, s). M/z (ES+) 153 (M+H+).Description 1 (3. 55 g, 25. 7 mmol), H2SO4 (2. 5 ml) and methanol(50 ml) were heated at 80 C for 3 days. The methanol was evaporated, the residue diluted with water(75 ml) and heated to 80 C. Solid sodium carbonate was added until effervescence ceased. The mixture was cooled and extracted with dichloromethane (2 x 100 ml). The combined organic layers were dried overMgS04 and concentrated to give the title compound as a beige solid (2.36 g, 60 percent). 'H NMR (500 MHz, DMSO) 5 8.24 (1H, s), 7.74 (1H, d, J5. 3), 7.46 (1H, d, J5.2), 6.67 (2H, brs), 3.83 (3H, s). M/z (ES+) 153 (M+H+).A mixture of 3-amino-isonicotinic acid (613 mg, 4.44 mmol), methanol (15 mL) and thionyl chloride (0.7 mL, 8.88 mmol) was stirred at reflux for 3 days.
Computed Properties
Molecular Weight:152.15
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:152.058577502
Monoisotopic Mass:152.058577502
Topological Polar Surface Area:65.2
Heavy Atom Count:11
Complexity:149
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 3-AMINO-ISONICOTINIC ACID METHYL ESTER
-
![China]()
CN
4 YRS
Business licensed Certified factoryManufactory Supplier of Cosmetics raw materials,Pesticide intermediate,Photoelectric material,pharmaceutical intermediates,Raw materials for food and health products,Polymer materials,Fine Chemicals,Synthetic customizationInquiryCAS No.: 55279-30-6Grade: Industrial GradeContent: 99% -
InquiryCAS No.: 55279-30-6Grade: Pharmaceutical GradeContent: 99%
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of PVC resin,pvc paste resin,melamineInquiryCAS No.: 55279-30-6Grade: Industrial GradeContent: 99%
Learn More Other Chemicals
-
Cyclopentanecarboxylic acid, 2-(hydroxyimino)-, methyl ester (9CI)
170016-09-8
-
3-CYCLOPROPYL-2-METHYL-3-OXO-PROPIONIC ACID ETHYL ESTER
21741-37-7
-
CYCLOPENTYL-CARBAMIC ACID PHENYL ESTER
58713-31-8
-
Cysteine, 2-methyl-, methyl ester (9CI) Formula
778548-47-3
-
D-Glucuronal 3,4-Diacetate Methyl Ester Formula
34296-99-6
-
2'-Deoxy-N-trimethylsilyl-3'-O-trimethylsilylcytidine 5'-phosphoric acid bis(trimethylsilyl) ester Formula
32645-72-0
-
4,6-Dichloro-1H-indole-2,3-dicarboxylic acid diethyl ester Structure
146012-24-0
-
2-[(2,6-Dichlorophenyl)sulfonyl]acetic acid ethyl ester Structure
1154228-17-7
-
What is Dibenzoic acid 2-ethylhexamethylene ester
25724-54-3
-
What is 1,4-DIBENZYL-7-PHENYL-6-THIOXO-1,4,7-TRIAZA-SPIRO[4.4]NON-8-ENE-9-CARBOXYLIC ACID ETHYL ESTER
885722-38-3
3-AMINO-ISONICOTINIC ACID METHYL ESTER
SDSRequest for Quotation