1,3-Benzodioxol-5-aMine, 6-iodo-

A solution of N-(6-iodobenzo[d][1, 3]dioxol-5-yl)acetamide (200 mg, 0.656 mmol) and NaOH (1.31 g, 32.8 mmol) in ethanol (26 mL) and water (6 mL) was heated to reflux with stirring for 4 h. A solution of N-(6-iodobenzo[d][1, 3]dioxol-5-yl)acetamide (200 mg, 0.656 mmol) and NaOH (1.31 g, 32.8 mmol) in ethanol (26 mL) and water (6 mL) was heated to reflux with stirring for 4 h. A solution of N-(6-iodobenzo[d][1, 3]dioxol-5-yl)acetamide (200 mg, 0.656 mmol) and NaOH (1.31 g, 32.8 mmol) in ethanol (26 mL) and water (6 mL) was heated to reflux with stirring for 4 h. The mixture was cooled and the solvent was removed under vacuum. The residue was partitioned between methylene chloride (100 mL) and water (100 mL). The organic layer was washed with water (2×100 mL), dried (MgSOTo a stirred solution of Intermediate 57 (5.0 g, 16.4 mmol) in EtOH (150 mL) was added a solution of sodium hydroxide (20.0 g, 500 mmol) in water (120 mL). The reaction mixture was stirred at 90A solution of N-(6-iodobenzo[d][1, 3]dioxol-5-yl)acetamide (200 mg, 0.656 mmol) and NaOH (1.31 g, 32.8 mmol) in ethanol (26 mL) and water (6 mL) was heated to reflux with stirring for 4 h. A solution of N-(6-iodobenzo[d][1, 3]dioxol-5-yl)acetamide (200 mg, 0.656 mmol) and NaOH (1.31 g, 32.8 mmol) in ethanol (26 mL) and water (6 mL) was heated to reflux with stirring for 4 h. A solution of N-(6-iodobenzo[d][1, 3]dioxol-5-yl)acetamide (200 mg, 0.656 mmol) and NaOH (1.31 g, 32.8 mmol) in ethanol (26 mL) and water (6 mL) was heated to reflux with stirring for 4 h. The mixture was cooled and the solvent was removed under vacuum. The residue was partitioned between methylene chloride (100 mL) and water (100 mL). The organic layer was washed with water (2×100 mL), dried (MgSOTo a stirred solution of Intermediate 57 (5.0 g, 16.4 mmol) in EtOH (150 mL) was added a solution of sodium hydroxide (20.0 g, 500 mmol) in water (120 mL). The reaction mixture was stirred at 90

Molecular Weight:263.03
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Exact Mass:262.94433
Monoisotopic Mass:262.94433
Topological Polar Surface Area:44.5
Heavy Atom Count:11
Complexity:155
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes