8-Bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol

413.15

332.23

DTXSID8043816

2933990090

23.47000

4.51440

light tan solid

447.5ºC at 760mmHg

224.4ºC

45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: ≥14 mg/mL

Desiccate at RT

3

Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME. (See all compounds classified as Dopamine Antagonists.)|Compounds that bind to and inhibit the action of ADENYLYL CYCLASES. (See all compounds classified as Adenylyl Cyclase Inhibitors.)

1H-3-benzazepin-7-ol, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-