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Home > Encyclopedia > 2,3-Diaminophenol

2,3-Diaminophenol

2,3-Diaminophenol structure

2,3-Diaminophenol 

structure
  • CAS No:

    59649-56-8

  • Formula:

    C6H8N2O

  • Chemical Name:

    2,3-Diaminophenol

  • Synonyms:

    2,3-DIAMINOPHENOL;2,3-Diaminophenolsulfate;2,3-Diaminophenol,97%;Phenol, 2,3-diaMino-;2,3-DiaMinophenol 97%

  • Categories:

    Pharmaceutical Intermediates  >  Heterocyclic Compound

Description

White to beige crystalline powder

2,3-Diaminophenol Basic Attributes

124.14

124.063660

2922299090

Characteristics

72.3

0.2

White Granular or Crystalline Powder or Crystals

1.3±0.1 g/cm3

161-165 °C(lit.)

303.6°C at 760 mmHg

137.4±23.7 °C

1.723

Safety Information

UN 3259 8/PG 2

3

20/22-36/37/38

26

Xn

P261-P305 + P351 + P338

H302-H315-H319-H332-H335

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 40 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

2,3-Diaminophenol Use and Manufacturing

1 l-(3-chlorophenyl)-6-hydroxy-3, 3-dimethyl-2, 3, 4, 5, 10, l 1-hexahydro- dibenzo, e] , 41diazepin- 1 -one (6).; Step l; A mixture of 2-amino-3-nitrophenol (10.0 g, 64.9 mmol), 10percent Pd/C in ethanol (150 mL), was hydrogenated at room temperature for 12 h. Then, the reaction mixture was degassed with nitrogen. The catalyst was removed by filtration and washed extensively with ethanol. The filtrate was evaporated to give 8.0 g (99percent) of the desired product as a black solid.Step 3. synthesis of 2, 3-diaminophenol (4). ; General procedure: To a solution of 4-amino-3-nitrophenol (28, 5.0 g, 32.44 mmol) was added cautiously Raney-Ni (1.0 g, wet weight) under N

Computed Properties

Molecular Weight:124.14
XLogP3:0.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Exact Mass:124.063662883
Monoisotopic Mass:124.063662883
Topological Polar Surface Area:72.3
Heavy Atom Count:9
Complexity:97.1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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