Sodium hypochlorite
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Sodium hypochlorite
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CAS No:
7681-52-9
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Formula:
ClHO.Na
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Chemical Name:
Sodium hypochlorite
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Synonyms:
Hypochlorous acid,sodium salt (1:1);Hypochlorous acid,sodium salt;Hyclorite;B-K Liquid;Sodium hypochlorite;Clorox;Antiformin;Sodium hypochlorite (NaOCl);Carrel-Dakin solution;Modified Dakin's solution;Milton;Chloros;Javex;Deosan;Neo-cleaner;Purin B;Klorocin;Dakin's solution;Sodium hypochloride;Parozone;Sodium hypochlorite (NaClO);Neoseptal CL;XY 12;Sunnysol 150;Javel water;Javelle water;Solutions,Dakin's;Hypure;Hypure N;Dispatch;Sodium chloride oxide (NaClO);Youxiaolin;AD Gel;Cloralex;Super White L;Dispatch (salt);AgClor 310;ActiPlus N 2818;Sodium oxychloride;Linely;Hishikurin S;Fox-Chlor;Purelox;Aron Clean;Parazone;Belizna;Comfor;Belkina;Tsurukuron;Sanrack P;Jomax Mold & Mildew Stain Remover;Baso agri+;Milton Sterilising Fluid;Javex 5;Nades;Aron Clean LB 10;Raverrack D;Purelex;Hypex;Histolith;DanKlorix;Tsurukuron N 40;Tsurukuron TW;Cloralex NL;Purelox S;Sodium chloride oxide;Deccoklor;Neolux Super;Sodium hypochlorite (Na(ClO));Lavanox;Kerrasol;ActiMaris Forte;Avol ACT;8007-59-8;56172-57-7;102324-78-7;227453-69-2;2243270-16-6
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CAS No:
Description
Sodium hypochlorite, NaOCl, is an air-unstable,pale green crystalline solid that is soluble in cold water, decomposes in hot water, and has a sweet aroma. It generally is available in one of two strengths. The household liquid bleach contains about 5.25 wt% NaCIO. The commercial product(sometimes called 15% bleach) contains 150g/L available chlorine. This is equivalent to about 13 wt% sodium hypochlorite. Sodium hypochlorite is used as a bleaching agent for paper pulp and textiles, as an oxidiz
Sodium hypochlorite appears as colorless or slightly yellow watery liquid with an odor of household bleach. Mixes with water. (USCG, 1999)|Liquid|CLEAR SLIGHTLY YELLOW SOLUTION WITH CHARACTERISTIC ODOUR.
Sodium hypochlorite appears as colorless or slightly yellow watery liquid with an odor of household bleach. Mixes with water. (USCG, 1999)|Sodium hypochlorite is generally used dissolved in water at various concentrations. Although available, solid sodium hypochlorite is not commercially used. Sodium hypochlorite solutions are clear, greenish to yellow liquids with an odor of chlorine. Calcium hypochlorite is a white solid that readily decomposes in water releasing oxygen and chlorine. It also has a strong chlorine odor. Neither compound occur naturally in the environment. Sodium and calcium hypochlorite are used primarily as bleaching agents or disinfectants. They are components of commercial bleaches, cleaning solutions, and disinfectants for drinking water and waste water purification systems and swimming pools.|Sodium hypochlorite is an inorganic sodium salt in which hypochlorite is the counterion. It is used as a bleaching and disinfecting agent and is commonly found in household bleach. It has a role as a disinfectant and a bleaching agent. It contains a hypochlorite.|Sodium Hypochlorite is a chlorine compound often used as a disinfectant or a bleaching agent. Sodium hypochlorite in 0.5% w/v solution is called Dakin's solution, and is used as an antiseptic to clean infected topical wounds.|It is used as an oxidizing and bleaching agent and as a disinfectant. (From Grant and Hackh's Chemical Dictionary, 5th ed)
Sodium hypochlorite Basic Attributes
74.44220
73.95350
231-668-3
DY38VHM5OD
0482|1119
1791
DTXSID8021276
C80658
Greenish yellow liquid|Anhydrous
D - Dermatologicals
2828900000
Characteristics
23.06000
0.57070
Sodium hypochlorite appears as colorless or slightly yellow watery liquid with an odor of household bleach. Mixes with water. (USCG, 1999)
1.25 g/mL at 20ºC
18 °C
111ºC
Solubility in water, g/l at 20°C: 293 (good)
2-8ºC
Vapour pressure, kPa at 20°C: 2 - 2.5
Skin contact with the solid hypochlorite pentahydrate or its concentrated solution can cause irritation. Ingestion may cause corrosion of mucous membranes and gastric perforation.
Anhydrous sodium hypochlorite is very explosive.
Disagreeable, sweetish odor
Does not produce red color with phenolphthalein; colorless or slightly yellow liq /Sodium hypochlorite soln, diluted/|ODOR OF HYPOCHLORITES; YELLOWISH CLEAR LIQ /ALKALINE/|Decomp by carbon dioxide from air /Pentahydrate/|Strong oxidizing agent usually stored and used in soln|For more Other Experimental Properties (Complete) data for SODIUM HYPOCHLORITE (10 total), please visit the HSDB record page.
Water soluble. Decomposes into chlorine and oxygen gases in hot water.
Salts, Basic
Strong Oxidizing Agent
Salts of hypochlorous acid, HClO. Generally toxic, irritants and powerful oxidizers, particularly in the presence of water or at higher temperature as they decompose to release oxygen and chlorine gases. On contact with urea they form the highly explosive NCl3 . When heated or on contact with acids, they produce highly toxic fumes of chlorine gas [Sax, 9th ed., 1996, p. 1905]. Can react with sulfuric acid to produce heat and chlorine gas.
Safety Information
III
8
UN 1791
2
R31; R34; R36/38; R36/37/38
S26; S36/37/39; S45; S50A; S28A; S36
NH3486300
C
Separated from combustible substances, reducing agents, acids and food and feedstuffs. See Chemical Dangers. Cool. Keep in the dark. Well closed. Store only in original container.
Stable. Contact with acids releases poisonous gas ( chlorine ). Light sensitive. Incompatible with strong acids, amines, ammonia, ammonium salts, reducing agents, metals, aziridine, methanol, formic acid, phenylacetonitrile.
P273-P280-P305 + P351 + P338
H315-H318-H400
SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
Chlorination of ethyleneimine with sodium hypochlorite gives the explosive compound 1-chloroethyleneimine.|Primary amines and calcium hypochlorite or sodium hypochlorite react to form normal chloroamines, which are explosive.|Hypochlorites react with urea to form nitrogen trichloride which explodes spontaneously in air. /Hypochlorites/|Contact in the drains of an effluent containing the hypochlorite with one containing ammonium salts & acid led to formation of nitrogen trichloride which decomp explosively. ... Cleaning a brewery tank with an acidified ammonium sulfate cleaning preparation, then sodium hypochlorite soln without intermediate rinsing, led to nitrogen trichloride formation & a violent explosion.|For more Hazardous Reactivities and Incompatibilities (Complete) data for SODIUM HYPOCHLORITE (10 total), please visit the HSDB record page.
Sodium hypochlorite is an indirect food additive for use only as a component of adhesives.
Morel C et al; Toxicological cards 157; Sodium hypochlorite; Cah Notes Doc 102: 139-42 (1981). A review that summarizes, with 12 references, the physical and chemical properties of sodium hypochlorite, hazards and its use, and current legislation in France affecting it. Recommendations are made for its storage and handling, and medical treatment in case of accidents.|Scribner HC; Handling of Bleaching Chemicals; Oxid Bleaching, Semin Notes Tech Assoc Pulp Pap Ind 95-102 (1981). The handling of bleaching chemicals, including sodium hypochlorite, is discussed.|Environment Canada; Tech Info for Problem Spills: Sodium Hypochlorite (Draft) (1985).
Special Hazards of Combustion Products: Store in a cool, dark place, away from combustible materials. Emits chlorine gas when burned. Behavior in Fire: May decompose, generating irritating chlorine gas. (USCG, 1999)|Not combustible. Gives off irritating or toxic fumes (or gases) in a fire. Heating will cause rise in pressure with risk of bursting.|Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.
|Danger|H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]|P260, P264, P273, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P391, P405, and P501|H290 (28.49%): May be corrosive to metals [Warning Corrosive to Metals]|P234, P260, P261, P264, P271, P273, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P363, P390, P391, P403+P233, P404, P405, and P501|Aggregated GHS information provided by 2436 companies from 61 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|P260, P261, P264, P271, P273, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P363, P391, P403+P233, P405, and P501|P260, P261, P264, P271, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P314, P321, P363, P403+P233, P405, and P501|P260, P261, P264, P270, P271, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P309+P311, P310, P312, P321, P363, P403+P233, P405, and P501|P260, P261, P264, P271, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P363, P403+P233, P405, and P501
Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)
Neutralizing Agents for Acids and Caustics: Sodium disulfite; hypo isulfite. (USCG, 1999)
Rubber gloves, goggles, self-contained breathing apparatus, plastic coveralls and boots. (USCG, 1999)|Personnel protection: ... Wear appropriate chemical protective gloves, boots and goggles /Hypochlorite soln (containing not more than 7% available chlorine, by wt)/
FIRE RISK IN CONTACT WITH ORG MATERIALS.|Not flammable /SRP: Acts as oxidizer with combustible material./
Anhydrous sodium hypochlorite is very explosive.
If material involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Use water in flooding quantities as fog. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. /Hypochlorite soln (containing more than 7% available chlorine, by wt)/|Cool exposed containers with water. /Monohydrate/
Environmental considerations-land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete; absorb bulk liquid with fly ash or cement powder; neutralize with agricultural lime (CaO), crushed limestone (CaCO3), or sodium bicarbonate (NaHCO3) /Sodium hypochlorite soln (Hypochlorite soln containing not more than 7% available chlorine, by wt)/|Environmental considerations- water spill: Neutralize with agricultural lime (CaO), crushed limestone (CaCO3), or sodium bicarbonate (NaHCO3); if dissolved, in region of 10 ppm or greater concn, apply activated carbon at 10 times the spilled amt; use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates. /Sodium hypochlorite soln (Hypochlorite soln containing not more than 7% available chlorine, by wt)/|Environmental considerations- air spill: Apply water spray or mist to knock down vapors. /Sodium hypochlorite soln (Hypochlorite soln containing not more than 7% available chlorine, by wt)/
If material not involved in fire: Keep material out of water sources and sewers; build dike to contain flow as necessary. /Hypochlorite soln (containing more than 7% available chlorine, by wt)/|Personnel protection: Avoid breathing vapors. Keep upwind. Avoid bodily contact with the material. Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amt of water or soap and water. ... If contact with the material anticipated, wear appropriate chemical protective clothing. /Hypochlorite soln (containing more than 7% available chlorine, by wt)/|SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.
/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Health: TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. /Hypochlorite solution; Hypochlorite solution, with more than 5% available Chlorine/|/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Fire or Explosion: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. /Hypochlorite solution; Hypochlorite solution, with more than 5% available Chlorine/|/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate enclosed areas. /Hypochlorite solution; Hypochlorite solution, with more than 5% available Chlorine/|/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible. /Hypochlorite solution; Hypochlorite solution, with more than 5% available Chlorine/|For more DOT Emergency Guidelines (Complete) data for SODIUM HYPOCHLORITE (8 total), please visit the HSDB record page.
No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.
It has a pronounced irritant effect on the skin.|Irritating to skin and eyes. /Monohydrate/
Personal protection: filter respirator for inorganic gases and vapours adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Ventilation. Collect leaking and spilled liquid in covered non-metallic containers as far as possible. Wash away remainder with plenty of water.|Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Ventilation. Collect leaking and spilled liquid in sealable non-metallic containers as far as possible. Then wash away with plenty of water. Do NOT absorb in saw-dust or other combustible absorbents.
Separated from acids. See Chemical Dangers. Cool. Keep in the dark. Well closed. Store only in original container.|Separated from combustible substances, reducing agents, acids and food and feedstuffs. See Chemical Dangers. Cool. Keep in the dark. Well closed. Store only in original container.
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.
The substance is irritating to the eyes, skin, respiratory tract and digestive tract.|The substance is corrosive to the eyes, skin, respiratory tract and digestive tract. Inhalation may cause lung oedema, but only after initial corrosive effects on eyes and/or airways have become manifest. The effects may be delayed. Medical observation is indicated.
Repeated or prolonged contact with skin may cause dermatitis.
PREVENT GENERATION OF MISTS!|STRICT HYGIENE! IN ALL CASES CONSULT A DOCTOR!
Use ventilation.|Use ventilation, local exhaust or breathing protection.
Protective gloves.|Protective gloves. Protective clothing.
Wear safety spectacles.|Wear face shield or eye protection in combination with breathing protection.
Sodium hypochlorite is generally used dissolved in water at various concentrations. Although available, solid sodium hypochlorite is not commercially used. Sodium hypochlorite solutions are clear, greenish to yellow liquids with an odor of chlorine. Calcium hypochlorite is a white solid that readily decomposes in water releasing oxygen and chlorine. It also has a strong chlorine odor. Neither compound occur naturally in the environment. Sodium and calcium hypochlorite are used primarily as bleaching agents or disinfectants. They are components of commercial bleaches, cleaning solutions, and disinfectants for drinking water and waste water purification systems and swimming pools.
Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 100 lb or 45.4 kg. The toll free number of the NRC is (800) 424-8802; In the Washington D.C. metropolitan area (202) 426-2675. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b).
Toxicity
... Pulmonary edema can occur from chlorine vapors developing after mixing clorox, a 5.25% soln of sodium hypochlorite, and Saniflush (80% NaHSO4).
LD50 Rat oral 8.91 g/kg|LD50 Mouse oral 5800 mg/kg
Drug Information
Disinfectants; Oxidants|For surgical purposes, diluted sodium hypochlorite soln is used; it contains 0.45 to 0.5% sodium hypochlorite and it may be further diluted 1:3. ... It is used to loosen and help dissolve and deodorize necrotic tissue. ... Diluted sodium hypochlorite soln may be used to irrigate ragged or dirty wounds, as an antiseptic in certain peritoneal dialysis system.|IT WAS ONCE WIDELY USED TO TREAT SUPPURATING WOUNDS, BUT HAS A SOLVENT ACTION ON BLOOD CLOTS AND THUS DELAYS CLOTTING.|For prophylaxis of epidermophytosis, diluted sodium hypochlorite soln is ... used as a foot bath. Soln is also a deodorant. /Sodium hypochlorite soln, diluted/|MEDICATION (VET): Antiseptic for wound irrigation /Sodium hypochlorite, diluted/
For surgical purposes, diluted sodium hypochlorite soln is used; it contains 0.45 to 0.5% sodium hypochlorite and it may be further diluted 1:3. ... It is used to loosen and help dissolve and deodorize necrotic tissue. ... It is irritating to the skin unless rinsed off promptly.|Topically applied hypochlorites may dissolve blood clots and cause bleeding. Sodium hypochlorite could interfere with the Clinistix and Labstix qualitative urine tests for glucose to produce false positive results. ... Traces of sodium hypochlorite soln adhering to utensils for preparing feeds of pooled human milk for premature infants incr dietary sodium intake by 50% in a series of 9 paired estimations.
Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity. Disinfectants are classed as complete, destroying SPORES as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms. They are distinguished from ANTISEPTICS, which are local anti-infective agents used on humans and other animals. (From Hawley's Condensed Chemical Dictionary, 11th ed) (See all compounds classified as Disinfectants.)|Electron-accepting molecules in chemical reactions in which electrons are transferred from one molecule to another (OXIDATION-REDUCTION). (See all compounds classified as Oxidants.)
Trichloroacetic acid was found in the gut contents & plasma of fasted & nonfasted rats 1 hr after dosing with sodium hypochlorite. Thus, the formation is not dependent on the interaction of sodium hypochlorite with foreign organic material in the gut. Dichloroacetic acid was also found in all treated animals. Chloroform generally was present when trichloroacetic acid was detected. Dichloroacetonitrile was found in the gut contents of 2 of 3 nonfasted rats treated with sodium hypochlorite. Addition of 8 mg sodium hypochlorite/ml to nonfasted rat gut contents in vitro produced dichloroacetic acid, trichloroacetic acid, dichloroacetonitrile, & trichloroacetonitrile.
ITS TOXIC EFFECT IS DUE TO PRESENCE OF CHLORINE.
INHALATION: Will produce severe bronchial irritation and pulmonary edema. INGESTION: burning of mouth, nausea and vomiting, delirium, coma. EYES & SKIN: can be irritating if contact is maintained. (USCG, 1999)|Corrosives
INHALATION: Sips of milk or other demulcent. EYES: Flush with plenty of water for 15 minutes. SKIN: Wash contaminated area with soap and water. (USCG, 1999)
Fresh air, rest. Refer for medical attention.|Fresh air, rest. Half-upright position. Artificial respiration may be needed. Administration of oxygen may be needed. Refer immediately for medical attention.
First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Refer for medical attention .|First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Refer immediately for medical attention.
Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer for medical attention.|Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer immediately for medical attention.
Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Do not attempt to neutralize. /Hypochlorite and related cmpds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who unconscious or in respiratory arrest. Early intubation, at the first signs of upper airway obstruction, may be necessary. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W TKO /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. consider vasopressors if hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Hypochlorite and related cmpds/
SYMPTOMATOLOGY: 1. PAIN & INFLAMMATION OF MOUTH, PHARYNX, ESOPHAGUS, & STOMACH. EROSION OF MUCOUS MEMBRANES, CHIEFLY OF STOMACH. 2. VOMITING ... HEMORRHAGE ... 3. CIRCULATORY COLLAPSE, WITH COLD & CLAMMY SKIN, CYANOSIS, & SHALLOW RESPIRATIONS. 4. CONFUSION, DELIRIUM, COMA. 5. EDEMA OF PHARYNX, GLOTTIS & LARYNX, WITH STRIDOR & OBSTRUCTION. 6. PERFORATION OF ESOPHAGUS OR STOMACH, WITH MEDIASTINITIS OR PERITONITIS. 7. INHALATION OF HYPOCHLOROUS ACID FUMES CAUSES SEVERE RESP TRACT IRRITATION & PULMONARY EDEMA. 8. SKIN CONTACT MAY CAUSE VESICULAR ERUPTIONS AND ECZEMATOID DERMATITIS. /HYPOCHLORITE/|INGESTION OF LETHAL DOSE OF SODIUM HYPOCHLORITE HAD CORROSIVE EFFECT & METHEMOGLOBINEMIA WAS PRESENT.|... An 18 month old girl who swallowed a "few tablespoons" /of liquid household bleach/ and immediately coughed, choked and vomited. Gastric lavage with a weak vinegar solution was performed within 10 min. Promptly thereafter she became lethargic and was admitted to a local hospital in a state of coma. Her temp was 103.2 °F, pulse 160, respirations 88, and blood pressure unobtainable. Rales and rhonchi were audible, & clonic convulsive movements persisted until death, which occurred, in spite of vigorous treatment, 19 hr after ingestion. Postmortem exam revealed focal necrosis, hemorrhage, and superficial erosion of the gastric mucosa, but the presumptive cause of death was an acute tracheobronchitis, & obstructive atelectasis secondary to bronchial exudates. /Hypochlorite/|A 61 yr old woman was completing a hemodialysis treatment when routine cleaning of the hemodialysis machine was started. Approx 2 l of undiluted sodium hypochlorite cleaning soln was added to the dialysis bath. For less than 2 min the chlorox soaked membrane was in contact with the blood returning to the pt. This led to massive hemolysis, hyperkalemia, cyanosis, & cardiopulmonary arrest.|For more Human Toxicity Excerpts (Complete) data for SODIUM HYPOCHLORITE (9 total), please visit the HSDB record page.
Antiformin
The substance can be absorbed into the body by inhalation of its aerosol.|Serious local effects by all routes of exposure.
Cough. Sore throat.|Burning sensation. Cough. Laboured breathing. Shortness of breath. Sore throat. Symptoms may be delayed.
Redness. Pain.|Redness. Skin burns. Pain. Blisters.
Redness. Pain.|Redness. Pain. Severe burns.
Sodium hypochlorite Use and Manufacturing
... Sanfourche, Gardent, Bull Soc Chim (4) 35, 1089 (1924); Schmeisser in Handbook of Preparative Inorganic Chemistry Vol 1, G Brauer, ed (Academic Press, NY, 2nd ed, 1963) pp 309-310. Anhydrous sodium hypochlorite may be obtained by freeze-drying in vacuum (over concn sulfuric acid). Addition of chlorine to cold dilute solution of sodium hydroxide.|Soln of sodium hypochlorite containing 0.45-0.50 g of the salt in 100 ml. Prepd by diluting with distilled water a soln of sodium hypochlorite, adding a 5% soln of sodium bicarbonate, nad adjusting to proper strength and concn according to procedure described in N.F. May be prepared also from 15.4 g chlorinated lime (30% available chlorine), 7.7 g anhydrous sodium carbonate, and 6.4 g sodium bicarbonate per liter; this soln is then adjusted ... /Sodium hypochlorite soln, diluted/
Sodium hypochlorite is used for water purification, as disinfectant, pulp bleaching, etc., and chloramine is used in the pharmaceutical industry.
ANTIMICROBIAL PESTICIDE
Agricultural products (non-pesticidal)
1,000,000,000 - 5,000,000,000 lb|(1972) 5.77X10+10 G|(1975) 6.49X10+10 G
USEPA/OPP Pesticide Code 014703; Trade Names: Antiformin, B-K liquid, Chlorox, Dakin's solution, Hychlorite, Milton, Mera Industries 2MOM3B, Chloros, Javelle water, Piochlor, Purex.|Modified Dakin's soln; surgical chlorinated soda solution; Carrel-Dakin soln. /Sodium hypochlorite diluted/|Eau de Labarraque; Clorox; Dazzle /aq soln/|Strongly alkaline soln of sodium hypochlorite; 100 ml contains 5.68 g active chlorine, 7.8 g sodium hydroxide, 32 g sodium bicarbonate. /Sodium hypochlorite soln, alkaline/|For more Formulations/Preparations (Complete) data for SODIUM HYPOCHLORITE (10 total), please visit the HSDB record page.
Agriculture, forestry, fishing and hunting|Hypochlorous acid, sodium salt (1:1): ACTIVE|IT IS OF PRIMARY IMPORTANCE THAT STRENGTH OF ... /DILUTED SODIUM HYPOCHLORITE/ BE ACCURATELY ADJUSTED & IT SHOULD BE RETESTED IF KEPT FOR MORE THAN A FEW DAYS.
Sodium hypochlorite solution pesticide formulations by sodium hypochlorite arsenious oxide titration method (method 935.07).|SODIUM HYPOCHLORITE CONCN IN WASTEWATER SAMPLES DETERMINED BY MEASURING ABSORBANCY @ 270-330 NM.|EPA Method 200.7: An Inductively Coupled Plasma - Atomic Emission Spectrophotmetric method for the determination of dissolved, suspended, or total elements in drinking water, surface water, and domestic and industrial wastewaters, is described. Sodium is analyzed at a wavelength of 588.995 nanometers and has an estimated detection limit of 29 ug/l. /Sodium/
Agrochemicals -> Bactericides|Human drugs -> Rare disease (orphan)|Health Hazards -> Corrosives
Computed Properties
Molecular Weight:74.44
Hydrogen Bond Acceptor Count:1
Exact Mass:73.9535366
Monoisotopic Mass:73.9535366
Topological Polar Surface Area:23.1
Heavy Atom Count:3
Complexity:4.8
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Price Analysis
- Data: 2026-07-23
- Price: 5300.00Yuan/mt
- Change: 0
Drug Function and Efficacy
Antimicrobial and bleaching agent; used for disinfection and wound cleansing due to its oxidative action
Registered Holders
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Fuchen (Tianjin) Chemical Reagent Co., Ltd.
Inactive
China
-
Chengdu HUAYI Pharmaceutical Excipients Manufacturing Co., Ltd.
Inactive
China
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