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Home > Encyclopedia > Cellulose

Cellulose

pharmaceutical raw materials
Cellulose structure

Cellulose 

structure
  • CAS No:

    9004-34-6

  • Chemical Name:

    Cellulose

  • Synonyms:

    Cellulose;Cellulose 248;Cellulose crystalline;Kingcot;Rayophane;Solka-fil;Pyrocellulose;α-Cellulose;Avicel;Tomofan;Cupricellulose;Tunicin;MN-Cellulose;Celufi;β-Amylose;Cepo;Cepo S 20;Rayweb Q;Chromedia CC 31;Chromedia CF 11;Cepo S 40;Cepo CFM;Sulfite cellulose;Solka-Floc BW;Elcema P 050;Elcema P 100;Elcema F 150;Elcema G 250;Avicel PH 101;Solka-Floc;Cellex MX;Avicel 101;Avicel 102;Sigmacell;Avicel PH 105;Solka-Floc BW 20;Whatman CC 31;Rexcel;Solka-Floc BW 2030;Solka-Floc BW 200;Solka-Floc BW 100;Spartose OM 22;LA 01;Arbocel BC 200;Fresenius D 6;Arbocel;Heweten 10;KC Flock W 200;Rehocel 1200;Cemirom;Whatman 41;Sigmacell 20;Sigmacell 100;Solka-Floc SW 40;Sigmacell 50;Avicel SF;Plastics,cellulosic;Avicel PH 102;Somicel F;Somicel Z;Tomcel T;Technocel 30;Technocel 50F;Emcocel;CF 11;KC Flock W 300;KC Flock W 250;Pulp-Flock W 4;Arbocel B 600/30;Heweten 40;Solka-Floc BW 300;Crystalline cellulose;Avicel PH 302;Avicel PH-M 06;Technocel 100;Daicel 500;Avicel PH 301;Pulp-Flock W 1;Pulp-Flock W 5;KC Flock W 400;Arbocel BE 600/30;Arbocel BE 600;Arbocel BWW 40;Arbocel DC 1000;Avicel TG 101;Avicel 2330;Avicel TG-D;Solka-Floc BW 200NF;CP 60;Alphafloc;MFTs-I;MFTs-V;Perloza MT 750;Arbocel B 820C;Arbocel TP 40;Arbocel FD 00;Technocel 300BL;Arbocel B 00;Neocel;Arbocel BE 600/20;Solka-Floc BW 300FCC;Bellfine D 10;Technocel 150D;Heweten 12;RC beads S-type;Divicell;Solka-Floc 40;Avicel 2331;9012-19-5;9037-50-7;9076-30-6;12656-52-9;39394-43-9;51395-76-7;58968-67-5;61991-21-7;61991-22-8;67016-75-5;67016-76-6;68073-05-2;70225-79-5;74623-16-8;75398-83-3;77907-70-1;84503-75-3;89468-66-6;99331-82-5;137261-76-8;152231-69-1;189398-86-5;196316-75-3;209533-95-9;231290-83-8;324745-49-5;358787-62-9;906542-14-1;1161712-52-2;1374408-52-2;1621420-37-8;1873279-80-1;2095812-59-0;2243384-02-1;2243384-04-3;2409008-33-7;2618568-52-6

  • Categories:

    Cosmetic Ingredient  >  Emulsion Stabilising

Description

white powder Microcrystalline cellulose and carboxymethylcellulose sodium occurs as a white or off-white odorless and tasteless hygroscopic powder containing 5–22% sodium carboxymethylcellulose. It is a water-dispersible organic hydrocolloid. Microcrystalline cellulose is a purified, partially depolymerized cellulose that occurs as a white, odorless, tasteless, crystalline powder composed of porous particles. It is commercially available in different particle sizes and moisture grades that have


Cellulose is an odorless, white powdery fibers. Density: 1.5 g/cm3. The biopolymer composing the cell wall of vegetable tissues. Prepared by treating cotton with an organic solvent to de-wax it and removing pectic acids by extration with a solution of sodium hydroxide. The principal fiber composing the cell wall of vegetable tissues (wood, cotton, flax, grass, etc.). Technical uses depend on the strength and flexibility of its fibers. Insoluble in water. Soluble with chemical degradation in sulfuric acid, and in concentrated solutions of zinc chloride. Soluble in aqueous solutions of cupric ammonium hydroxide (Cu(NH3)4(OH)2).|WetSolid|Odorless, white substance.|Odorless, white substance. [Note: The principal fiber cell wall material of vegetable tissues (wood, cotton, flax, grass, etc.).]


Cellulose is an odorless, white powdery fibers. Density: 1.5 g/cm3. The biopolymer composing the cell wall of vegetable tissues. Prepared by treating cotton with an organic solvent to de-wax it and removing pectic acids by extration with a solution of sodium hydroxide. The principal fiber composing the cell wall of vegetable tissues (wood, cotton, flax, grass, etc.). Technical uses depend on the strength and flexibility of its fibers. Insoluble in water. Soluble with chemical degradation in sulfuric acid, and in concentrated solutions of zinc chloride. Soluble in aqueous solutions of cupric ammonium hydroxide (Cu(NH3)4(OH)2).|A disaccharide consisting of two glucose units in beta (1-4) glycosidic linkage. Obtained from the partial hydrolysis of cellulose.

Cellulose Basic Attributes

2

2.01588

200-716-5|232-674-9|238-691-8

2559

DTXSID1023233|DTXSID3045984|DTXSID3050492|DTXSID50873004

48239090

Characteristics

190 Ų

4.75

powder

1.04 g/cm3 @ Temp: 20 °C

76-78 °C @ Solvent: Acetone, Chloroform

237.6±35.0 °C at 760 mmHg

164 °C

n20/D 1.504

H2O: insoluble

room temp

0 mm Hg (approx) (NIOSH, 2016)|0 mmHg (approx)

LD50 orally in Rabbit: > 5000 mg/kg LD50 dermal Rabbit > 2000 mg/kg

No rapid reaction with air No rapid reaction with water

Alcohols and Polyols

CELLULOSE is combustible. Incompatible with strong oxidizing agents including bromine pentafluoride, sodium nitrate, fluorine, perchlorates, perchloric acid, sodium chlorate, magnesium perchlorate, F2, zinc permanganate, sodium nitrite, sodium nitrate, sodium peroxide. Nitration with a mixture of nitric and sulfuric acids produces cellulose nitrates (celluloid pyroxylin, soluble pyroxyline, guncotton) which are flammable or explosive.

Combustible Solid

Safety Information

NONH for all modes of transport

3

37

24/25

FJ5950200

Xi

Stable. Combustible. Incompatible with strong oxidizing agents.

Not Classified

Skin: No recommendation is made specifying the need for personal protective equipment for the body. Eyes: No recommendation is made specifying the need for eye protection. Wash skin: No recommendation is made specifying the need for washing the substance from the skin (either immediately or at the end of the work shift). Remove: No recommendation is made specifying the need for removing clothing that becomes wet or contaminated. Change: No recommendation is made specifying the need for the worker to change clothing after the work shift. (NIOSH, 2016)|(See protection codes)

Drug Information

Exposure Routes: inhalation, skin and/or eye contact Symptoms: Irritation eyes, skin, mucous membrane Target Organs: Eyes, skin, respiratory system (NIOSH, 2016)

Eye: If this chemical contacts the eyes, immediately wash the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately. Contact lenses should not be worn when working with this chemical. Skin: If this chemical contacts the skin, wash the contaminated skin with soap and water. Breathing: If a person breathes large amounts of this chemical, move the exposed person to fresh air at once. Other measures are usually unnecessary. (NIOSH, 2016)|(See procedures)

4 O beta D Glucopyranosyl D glucopyranose

inhalation, skin and/or eye contact

irritation eyes, skin, mucous membrane

Eyes, skin, respiratory system

Cellulose Use and Manufacturing

Uses

1. High purity cellulose powders for partition chromatography.
2. ACCEL-101 is most widely used for direct compression tableting and wet granulation.ACCEL-102 has similar compression properties to ACCEL-101. However, it has larger particle size and therefore, may be of value in improving the flow if fine powders.ACCEL


Adhesives and sealant chemicals

.alpha.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-: ACTIVE|D-Glucose, 4-O-.beta.-D-glucopyranosyl-: ACTIVE|.beta.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-: ACTIVE|D-Glucose, 4-O-.beta.-D-galactopyranosyl-: ACTIVE|Primary metal manufacturing|D-Glucose, 4-O-.alpha.-D-glucopyranosyl-: ACTIVE|Cellulose: ACTIVE|XU - indicates a substance exempt from reporting under the Chemical Data Reporting Rule, (40 CFR 711).

EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives|Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern|Cosmetics -> Absorbent; Bulking; Masking; Moisturising; Opacifying; Skin conditioning; Viscosity controlling

Food Additives -> ANTICAKING_AGENT; EMULSIFIER; STABILIZER;|Food Additives -> ANTICAKING_AGENT; EMULSIFIER; TEXTURIZER; THICKENER;

Computed Properties

Molecular Weight:342.30
XLogP3:-4.7
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:4
Exact Mass:342.11621151
Monoisotopic Mass:342.11621151
Topological Polar Surface Area:190
Heavy Atom Count:23
Complexity:382
Undefined Atom Stereocenter Count:10
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

The specific pharmacological effect is not clear from the above information

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Registered Holders

  • Luogaite Health Pharmaceuticals (Shanghai) Co., Ltd.

    China China
    Active
  • Ruisheng Pharmaceutical (Henan) Co., Ltd.

    China China
    Active
  • ZHUHAI TOPCHAIN PHARMACEUTICAL CO LTD

    United States United States
    Active

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