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Home > Encyclopedia > Ginsenoside Rg3

Ginsenoside Rg3

pharmaceutical raw materials
Ginsenoside Rg3 structure

Ginsenoside Rg3 

structure
  • CAS No:

    14197-60-5

  • Formula:

    C42H72O13

  • Chemical Name:

    Ginsenoside Rg3

  • Synonyms:

    β-D-Glucopyranoside,(3β,12β)-12,20-dihydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-;Dammar-24-ene-12β,20-diol,3β-[(2-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-;Dammarane,β-D-glucopyranoside deriv.;(3β,12β)-12,20-Dihydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside;(20S)-Propanaxadiol;Ginsenoside Rg3;20(S)-Ginsenoside-Rg3;(3β,12β)-12,20-Dihydroxydammar-24-en-3-yl O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside;3-O-β-D-Glucopyranosyl-(1→2)-β-D-glucopyranosyldammar-24-ene-3β,12β,20S-triol;S-Ginsenoside Rg3;Ginsenoside 20-Rg3;20S-Ginsenoside Rg3;20(S)-Rg3;Ginsenoside Rg3s;11019-45-7;12770-19-3;47891-53-2;195711-65-0

  • Categories:

    Biochemical Engineering  >  Plant Extracts

Description

Ginsenoside Rg3 is the main component of Red ginseng. Ginsenoside Rg3 inhibits Na+ and hKv1.4 channel with IC50s of 32.2±4.5 and 32.6±2.2 μM, respectively. Ginsenoside Rg3 also inhibits Aβ levels, NF-κB activity, and COX-2 expression.

Ginsenoside Rg3 Basic Attributes

785.02

785.01

29214210

Characteristics

219 Ų

2.14900

white to beige

1.3±0.1 g/cm3

146-147 °C

913.4°C at 760 mmHg

489.0±34.3 °C

1.594

DMSO: ≥5mg/mL

2-8°C

0mmHg at 25°C

Safety Information

II

6.1

UN 3442 6.1/PG 2

3

22

S28-S36/37-S45-S60-S61-S28A

LY9537300

Xn

H302

Ginsenoside Rg3 Use and Manufacturing

Methods of Manufacturing

10 mg of ginsenoside Rd obtained in the above procedure was precisely taken and 5 samples were placed in 2 ml of a cryogenic sterile vial, and the lid (Screw Stopper & silicone ring) was closed and placed in a 125 ml bottle.Then, the above-mentioned optical filter bottle was placed in a sterilizer (SANYO autoclave, MLS-3780 model) and the mixture was steamed for 2 hours under a pressure of 0.13 to 0.15 MPa at 120 and After 2 hours, only one of the five samples was taken out, and the remaining was subjected to further steaming at the same temperature and pressure conditions. By repeating the above procedure, the boiled water was obtained according to the time (2 hours, 4 hours, 6 hours, 8 hours and 10 hours) and the contents of the ginsenosides Rd, Rg3-S and Rg3-R are shown in Table 2 by HPLC analysis.

Uses

Ginsenoside Rg3 is the main component of total ginsenosides, accounting for about 4.7%, and has an effect on endothelial relaxation of the aorta.

Drug Function and Efficacy

Inhibits HIV reverse transcriptase activity

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

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