7-Chloro-4-hydroxy-3-(3-phenoxyphenyl)-2(1H)-quinolinone
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7-Chloro-4-hydroxy-3-(3-phenoxyphenyl)-2(1H)-quinolinone
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CAS No:
142326-59-8
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Formula:
C21H14ClNO3
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Chemical Name:
7-Chloro-4-hydroxy-3-(3-phenoxyphenyl)-2(1H)-quinolinone
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Synonyms:
2(1H)-Quinolinone,7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-;7-Chloro-4-hydroxy-3-(3-phenoxyphenyl)-2(1H)-quinolinone;L 701324
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CAS No:
7-Chloro-4-hydroxy-3-(3-phenoxyphenyl)-2(1H)-quinolinone Basic Attributes
363.79
363.79
I9WY146163
DTXSID00162016
Safety Information
3
36/37/38
26-36
Xi
|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Drug Information
Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here. (See all compounds classified as Anti-Anxiety Agents.)|Drugs used to prevent SEIZURES or reduce their severity. (See all compounds classified as Anticonvulsants.)|Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. (See all compounds classified as Antidepressive Agents.)|Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists. (See all compounds classified as Excitatory Amino Acid Antagonists.)
7-chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(1H)-quinolone
Computed Properties
Molecular Weight:363.8
XLogP3:4.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:363.0662210
Monoisotopic Mass:363.0662210
Topological Polar Surface Area:58.6
Heavy Atom Count:26
Complexity:558
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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