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Home > Encyclopedia > 7-Chloro-4-hydroxy-3-(3-phenoxyphenyl)-2(1H)-quinolinone

7-Chloro-4-hydroxy-3-(3-phenoxyphenyl)-2(1H)-quinolinone

7-Chloro-4-hydroxy-3-(3-phenoxyphenyl)-2(1H)-quinolinone structure

7-Chloro-4-hydroxy-3-(3-phenoxyphenyl)-2(1H)-quinolinone 

structure
  • CAS No:

    142326-59-8

  • Formula:

    C21H14ClNO3

  • Chemical Name:

    7-Chloro-4-hydroxy-3-(3-phenoxyphenyl)-2(1H)-quinolinone

  • Synonyms:

    2(1H)-Quinolinone,7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-;7-Chloro-4-hydroxy-3-(3-phenoxyphenyl)-2(1H)-quinolinone;L 701324

Description

7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-1H-quinolin-2-one is a member of quinolines.

7-Chloro-4-hydroxy-3-(3-phenoxyphenyl)-2(1H)-quinolinone Basic Attributes

363.79

363.79

I9WY146163

DTXSID00162016

Characteristics

5.1 (LogP)

1.389±0.06 g/cm3

308 °C

584.7±50.0 °C(Predicted)

4.50±1.00

Safety Information

3

36/37/38

26-36

Xi

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here. (See all compounds classified as Anti-Anxiety Agents.)|Drugs used to prevent SEIZURES or reduce their severity. (See all compounds classified as Anticonvulsants.)|Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. (See all compounds classified as Antidepressive Agents.)|Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists. (See all compounds classified as Excitatory Amino Acid Antagonists.)

7-chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(1H)-quinolone

Computed Properties

Molecular Weight:363.8
XLogP3:4.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:363.0662210
Monoisotopic Mass:363.0662210
Topological Polar Surface Area:58.6
Heavy Atom Count:26
Complexity:558
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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