CMI977
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CMI977
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CAS No:
175212-04-1
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Formula:
C16H19FN2O4
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Chemical Name:
CMI977
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Synonyms:
CMI977;LDP977;Urea, N-[4-[(2S,5S)-5-[(4-fluorophenoxy)methyl]tetrahydro-2-furanyl]-3-butyn-1-yl]-N-hydroxy-
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CAS No:
Description
MLN-977 is a small molecule compound that inhibits the production of leukotrienes, especially 5-lipoxygenase. It is developed by PharmaEngine to treat asthma and chronic obstructive pulmonary disease.
Drug Information
Investigated for use/treatment in asthma and chronic obstructive pulmonary disease (COPD).
MLN977 is a second generation compound in the class of asthma therapies known as 5-LO inhibitors, which block the production of leukotrienes. Leukotrienes are major mediators of the inflammatory response.
Computed Properties
Molecular Weight:322.33
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:322.13288525
Monoisotopic Mass:322.13288525
Topological Polar Surface Area:85
Heavy Atom Count:23
Complexity:454
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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