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Tiapamil

Tiapamil structure

CAS No:
57010-31-8
Formula:
C26H37NO8S2
Chemical Name:
Tiapamil
Synonyms:
1,3-Dithiane-2-propanamine,2-(3,4-dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-N-methyl-,1,1,3,3-tetraoxide;Tiapamil
Categories:
Organic Chemistry > Amides

Description

Tiapamil is a member of benzenes and an organic amino compound.|A phenylethylamine derivative that acts as a calcium antagonist showing hemodynamic effects in patients with acute myocardial infarction.

Tiapamil Basic Attributes

Molecular Weight：

555.70400

Exact Mass：

555.70

EC Number：

260-510-6

UNII：

0ONY823T4J

DSSTox ID：

DTXSID10205620

Characteristics

PSA：

125.20000

XLogP3：

5.22340

Density：

1.235g/cm3

Melting Point：

147-148 °C @ Solvent: Dichloromethane, Methanol

Boiling Point：

759ºC

Flash Point：

407.9ºC

Refractive Index：

1.547

Drug Information

MeSH：

A class of drugs that act by selective inhibition of calcium influx through cellular membranes. (See all compounds classified as Calcium Channel Blockers.)

MeSH Entry Terms：

dimeditiapramine

Computed Properties

Molecular Weight:555.7
XLogP3:3.1
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:12
Exact Mass:555.19605949
Monoisotopic Mass:555.19605949
Topological Polar Surface Area:125
Heavy Atom Count:37
Complexity:880
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes