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Home > Encyclopedia > 1-(2-Aminoethyl)-7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one

1-(2-Aminoethyl)-7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one

1-(2-Aminoethyl)-7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one structure

1-(2-Aminoethyl)-7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one 

structure
  • CAS No:

    17617-59-3

  • Formula:

    C17H15ClFN3O

  • Chemical Name:

    1-(2-Aminoethyl)-7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one

  • Synonyms:

    2H-1,4-Benzodiazepin-2-one,1-(2-aminoethyl)-7-chloro-5-(2-fluorophenyl)-1,3-dihydro-;2H-1,4-Benzodiazepin-2-one,1-(2-aminoethyl)-7-chloro-5-(o-fluorophenyl)-1,3-dihydro-;1-(2-Aminoethyl)-7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one;1-(2-Aminoethyl)-7-chloro-1,3-dihydro-5-(2-fluorophenyl)-2H-1,4-benzodiazepin-2-one;7-Chloro-1-(2-aminoethyl)-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one;Didesethylflurazepam;Dideethylflurazepam;Dealkylflurazepam;N,N-Bisdesethylflurazepam

Description

Didesethylflurazepam is a primary amino compound resulting from the dealkylation of both ethyl groups of the anti-insomnia drug flurazepam. It is the major metabolite of flurazepam. It has a role as a GABAA receptor agonist, an anticonvulsant, an anxiolytic drug, a sedative and a drug metabolite. It is a 1,4-benzodiazepinone, a member of monofluorobenzenes, an organochlorine compound and a primary amino compound.

1-(2-Aminoethyl)-7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one Basic Attributes

331.77200

331.77

BUJ3JOD7XF

DTXSID80170093

2933990090

Characteristics

58.69000

2.82270

1.36g/cm3

552ºC

286.5ºC

1.641

3.75E-12mmHg at 25°C

Drug Information

1-(2-aminoethyl)-7-chloro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2-one

Computed Properties

Molecular Weight:331.8
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:331.0887680
Monoisotopic Mass:331.0887680
Topological Polar Surface Area:58.7
Heavy Atom Count:23
Complexity:473
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Guide of 1-(2-Aminoethyl)-7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one

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