(+)-Etodolac
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(+)-Etodolac
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CAS No:
87249-11-4
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Formula:
C17H21NO3
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Chemical Name:
(+)-Etodolac
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Synonyms:
Pyrano[3,4-b]indole-1-acetic acid,1,8-diethyl-1,3,4,9-tetrahydro-,(1S)-;Pyrano[3,4-b]indole-1-acetic acid,1,8-diethyl-1,3,4,9-tetrahydro-,(S)-;(1S)-1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid;(+)-Etodolic acid;S-Etodolac;RAK 592;(+)-(S)-Etodolac;(+)-Etodolac;(S)-(+)-Etodolac;(S)-(+)-Etodolic acid;147170-17-0
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CAS No:
Description
(S)-etodolac is the S-enantiomer of etodolac. It is a preferential inhibitor of cyclo-oxygenase 2 and a non-steroidal anti-inflammatory, whereas the enantiomer, (R)-etodolac, is inactive. The racemate is commonly used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. It has a role as a cyclooxygenase 2 inhibitor and a non-narcotic analgesic. It is an enantiomer of a (R)-etodolac.
Computed Properties
Molecular Weight:287.35
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:287.15214353
Monoisotopic Mass:287.15214353
Topological Polar Surface Area:62.3
Heavy Atom Count:21
Complexity:400
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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