Sipatrigine
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Sipatrigine
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CAS No:
130800-90-7
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Formula:
C15H16Cl3N5
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Chemical Name:
Sipatrigine
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Synonyms:
4-Pyrimidinamine,2-(4-methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)-;2-(4-Methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)-4-pyrimidinamine;BW 619C89;Sipatrigine;619C89;2-(4-Methyl-piperazin-1-yl)-5-(2,3,5-trichloro-phenyl)-pyrimidin-4-ylamine
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CAS No:
Drug Information
Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids. (See all compounds classified as Neuroprotective Agents.)|Drugs that inhibit the transport of neurotransmitters into axon terminals or into storage vesicles within terminals. For many transmitters, uptake determines the time course of transmitter action so inhibiting uptake prolongs the activity of the transmitter. Blocking uptake may also deplete available transmitter stores. Many clinically important drugs are uptake inhibitors although the indirect reactions of the brain rather than the acute block of uptake itself is often responsible for the therapeutic effects. (See all compounds classified as Neurotransmitter Uptake Inhibitors.)
4-amino-2-(4-methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)pyrimidine
Computed Properties
Molecular Weight:372.7
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:371.047129
Monoisotopic Mass:371.047129
Topological Polar Surface Area:58.3
Heavy Atom Count:23
Complexity:393
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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