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Home > Encyclopedia > 1-Methyl-4-phenylpyridinium

1-Methyl-4-phenylpyridinium

1-Methyl-4-phenylpyridinium structure

1-Methyl-4-phenylpyridinium 

structure
  • CAS No:

    48134-75-4

  • Formula:

    C12H12N

  • Chemical Name:

    1-Methyl-4-phenylpyridinium

  • Synonyms:

    Pyridinium,1-methyl-4-phenyl-;1-Methyl-4-phenylpyridinium;Cyperquat;1-Methyl-4-phenylpyridinium ion;1-Methyl-4-phenylpyridine ion(1+);N-Methyl-4-phenylpyridinium ion;N-Methyl-4-phenylpyridinium;MPP+;125910-57-8

Description

N-methyl-4-phenylpyridinium is a pyridinium ion that is N-methylpyridinium having a phenyl substituent at the 4-position. It has a role as a human xenobiotic metabolite, a herbicide, an apoptosis inducer and a neurotoxin.|An active neurotoxic metabolite of 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. The compound reduces dopamine levels, inhibits the biosynthesis of catecholamines, depletes cardiac norepinephrine and inactivates tyrosine hydroxylase. These and other toxic effects lead to cessation of oxidative phosphorylation, ATP depletion, and cell death. The compound, which is related to PARAQUAT, has also been used as an herbicide.

1-Methyl-4-phenylpyridinium Basic Attributes

170.23 g/mol

170.096974387 g/mol

R865A5OY8J

DTXSID4058106

Characteristics

3.9 Ų

Drug Information

Pesticides used to destroy unwanted vegetation, especially various types of weeds, grasses (POACEAE), and woody plants. Some plants develop HERBICIDE RESISTANCE. (See all compounds classified as Herbicides.)

1-methyl-4-phenylpyridin-1-ium is a known human metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

1 Methyl 4 phenylpyridine

Computed Properties

Molecular Weight:170.23
XLogP3:2.7
Rotatable Bond Count:1
Exact Mass:170.096974387
Monoisotopic Mass:170.096974387
Topological Polar Surface Area:3.9
Heavy Atom Count:13
Formal Charge:1
Complexity:141
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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