1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-prop-1-ynylpyrimidine-2,4-dione
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![1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-prop-1-ynylpyrimidine-2,4-dione structure](https://file.echemi.com/fileManage/upload/canonicalSmiles/20220812/68577069c8134084972acc5c5d5d84df.png "1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-prop-1-ynylpyrimidine-2,4-dione")
1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-prop-1-ynylpyrimidine-2,4-dione
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CAS No:
84558-93-0
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Formula:
C12H14N2O6
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Chemical Name:
1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-prop-1-ynylpyrimidine-2,4-dione
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Synonyms:
1-(beta-D-arabinofuranosyl)-5-(1-propynyl)uracil;5-propynyl-1-(beta-arabinofuranosyl)uracil;5-propynyl-araU;5-propynylarabinofuranosyluracil;882C;882C87;netivudine;PYaraU;NETIVUDINE;84558-93-0;UNII-F7K51T0Q1W;882C87;F7K51T0Q1W;2,4(1H,3H)-Pyrimidinedione, 1-beta-D-arabinofuranosyl-5-(1-propynyl)-;Netivudine [INN:BAN];5-Propynylarabinofuranosyluracil;PYaraU;BW882C87;DRG-0179;1-(beta-D-Arabinofuranosyl)-5-(1-propynyl)uracil;SCHEMBL1585773;CHEMBL1097615;DTXSID70233545;ZINC3794610;DB12606;1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-prop-1-ynylpyrimidine-2,4-dione;1-(beta-D-arabinofuranosyl)-5-propynyluracil;1-beta-D-Arabinofuranosyl-5-(1-propynyl)uracil;1-.beta.-D-Arabinofuranosyl-5-(1-propynyl)uracil;882C-87;Q27277769;1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-prop-1-ynyl-pyrimidine-2,4-dione
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CAS No:
Description
Netivudine has been used in trials studying the treatment of Chickenpox and HIV Infections.
1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-prop-1-ynylpyrimidine-2,4-dione Basic Attributes
282.25 g/mol
282.08518617 g/mol
F7K51T0Q1W
DTXSID70233545
Drug Information
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)
1-(beta-D-arabinofuranosyl)-5-(1-propynyl)uracil
Computed Properties
Molecular Weight:282.25
XLogP3:-1.2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:282.08518617
Monoisotopic Mass:282.08518617
Topological Polar Surface Area:119
Heavy Atom Count:20
Complexity:531
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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