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Home > Encyclopedia > 8-(1,4,5-triphenylimidazol-2-yl)oxyoctanoic acid

8-(1,4,5-triphenylimidazol-2-yl)oxyoctanoic acid

8-(1,4,5-triphenylimidazol-2-yl)oxyoctanoic acid structure

8-(1,4,5-triphenylimidazol-2-yl)oxyoctanoic acid 

structure
  • CAS No:

    89838-96-0

  • Formula:

    C29H30N2O3

  • Chemical Name:

    8-(1,4,5-triphenylimidazol-2-yl)oxyoctanoic acid

  • Synonyms:

    8-((1,4,5-triphenylimidazol-2-yl)oxy)octanoic acid;BMY 22389;BMY-22389;NAT 04-152;octimibate;Octimibate;89838-96-0;UNII-S0SIQ441YZ;8-(1,4,5-triphenylimidazol-2-yl)oxyoctanoic acid;S0SIQ441YZ;Octimibato;Octimibatum;Octimibate [INN];Octimibatum [Latin];Octimibato [Spanish];SCHEMBL382403;CHEMBL419952;DTXSID40237919;ZINC27092582;L000452;8-(1,4,5-Triphenylimidazol-2-yloxy)octanoic acid;8-((1,4,5-Triphenylimidazol-2-yl)oxy)octanoic acid;8-(1,4,5-triphenylimidazol-2-yl-oxy)-caprylic acid;Q27288412

Description

Octimibate is an acyl-Coenzyme A:cholesterol acyltransferase (ACAT) inhibitor with antilipidemic, antiatherosclerotic, and antithrombotic activity. In an animal model, inhibition of ACAT by octimibate increased HDL receptor activity and stimulated HDL-mediated cholesterol efflux from peritoneal macrophages.

8-(1,4,5-triphenylimidazol-2-yl)oxyoctanoic acid Basic Attributes

454.6 g/mol

454.22564282 g/mol

S0SIQ441YZ

DTXSID40237919

C91028

Characteristics

64.4 Ų

Drug Information

8-((1,4,5-triphenylimidazol-2-yl)oxy)octanoic acid

Computed Properties

Molecular Weight:454.6
XLogP3:7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:12
Exact Mass:454.22564282
Monoisotopic Mass:454.22564282
Topological Polar Surface Area:64.4
Heavy Atom Count:34
Complexity:582
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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