N-[2-(Fluoro-18F)ethyl]-2-hydroxy-N,N-dimethylethanaminium

Fluoroethylcholine (18F) is a member of cholines.|Fluorine F 18 Fluoroethylcholine is ethylcholine labeled with fluorine F 18, a positron-emitting isotope. Fluorine F 18 fluoroethylcholine incorporates into tumor cells through an active, carrier-mediated transport mechanism for choline and then is phosphorylated intracellularly by choline kinase, yielding a phosphoryl derivative, and finally is integrated into cellular phospholipids, probably primarily into a phosphatidyl derivative; concentration of this agent in tumor cells as various fluorine F 18 fluoroethylcholine derivatives enables tumor imaging using positron emission tomography (PET). Choline kinase, the enzyme responsible for the phosphorylation of choline, is frequently up-regulated in human tumor cell lines.

Molecular Weight:135.19
XLogP3:-0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:135.116301
Monoisotopic Mass:135.116301
Topological Polar Surface Area:20.2
Heavy Atom Count:9
Formal Charge:1
Complexity:75.5
Isotope Atom Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes