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Home > Encyclopedia > Lisuride maleate

Lisuride maleate

pharmaceutical raw materials
Lisuride maleate structure

Lisuride maleate 

structure
  • CAS No:

    19875-60-6

  • Formula:

    C20H26N4O.C4H4O4

  • Chemical Name:

    Lisuride maleate

  • Synonyms:

    Urea,N′-[(8α)-9,10-didehydro-6-methylergolin-8-yl]-N,N-diethyl-,(2Z)-2-butenedioate (1:1);Urea,3-(9,10-didehydro-6-methylergolin-8α-yl)-1,1-diethyl-,maleate (1:1);Urea,N′-[(8α)-9,10-didehydro-6-methylergolin-8-yl]-N,N-diethyl-,(Z)-2-butenedioate (1:1);Ergoline,urea deriv.;Indolo[4,3-fg]quinoline,urea deriv.;Lysenyl hydrogen maleate;Lysenyl bimaleate;Lisuride hydrogen maleate;Lysenyl;Lisuride maleate;Cuvalit;Apodel;Dopergin;Eunal;Revanil;39944-31-5

Description

An ergot derivative that acts as an agonist at dopamine D2 receptors (DOPAMINE AGONISTS). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (SEROTONIN RECEPTOR AGONISTS).

Lisuride maleate Basic Attributes

454.51900

454.22162007

243-387-3

UV1635N8XW

Characteristics

125.97000

2.88200

1.23g/cm3

200 °C (decomp)

603.4ºC at 760mmHg

318.7ºC

1.64E-14mmHg at 25°C

Safety Information

|Danger|H300 (100%): Fatal if swallowed [Danger Acute toxicity, oral]|P264, P270, P301+P310, P321, P330, P405, and P501|Aggregated GHS information provided by 26 companies from 2 notifications to the ECHA C&L Inventory.

Drug Information

Agents used in the treatment of Parkinson's disease. The most commonly used drugs act on the dopaminergic system in the striatum and basal ganglia or are centrally acting muscarinic antagonists. (See all compounds classified as Antiparkinson Agents.)|Drugs that bind to and activate dopamine receptors. (See all compounds classified as Dopamine Agonists.)|Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS. (See all compounds classified as Serotonin Receptor Agonists.)

Arolac

Lisuride maleate Use and Manufacturing

Human drugs -> Rare disease (orphan)

Computed Properties

Molecular Weight:454.5
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:454.22162007
Monoisotopic Mass:454.22162007
Topological Polar Surface Area:126
Heavy Atom Count:33
Complexity:663
Defined Atom Stereocenter Count:2
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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