Ethylhexylglycerin
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Ethylhexylglycerin
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CAS No:
70445-33-9
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Formula:
C11H24O3
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Chemical Name:
Ethylhexylglycerin
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Synonyms:
2-Propanediol, 3-[(2-ethylhexyl)oxy]-1;Glycerol α-(2-Ethylhexyl) Ether;Sensiva SC 50JP;liquid,100Ml;3-(2-ethylhexyloxy) propane-1,2-dio;Ethylhexyl Glycerin, (3-[2-(Ethylhexyl)Oxyl]-1,2-Propandiol);Sensiva SC 50;ETHYLHEXYLGLYCERIN
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CAS No:
Description
Ethylhexylglycerin is also named as 3-(2-Ethylhexoxy)propane-1,2-diol or octoxyglycerin. It is a glyceryl ether. It is used as a weak preservative, as skin conditioning agent with effective wetting ability. It is used with phenoxyethanol in cosmetics to obtain better protection against microbial growth.
Ethylhexylglycerin is a glycerol monoalkylether of defined structure and high purity,with a 2-ethylhexyl group bound to the primary hydroxyl function of the glycerol molecule. Due to the fact that it is a crystal-clear,colourless liquid with a slightly characteristic odour it is well suited for the use in cosmetic products. Although it is less soluble in water(<0.1% at 25℃),it is more easily soluble in most common cosmetic alcohols and glycols as well as oils.Ethylhexylglycerin is rather stable, e.g. against hydrolysis and elevated temperatures and compatible with cosmetic ingredients.Ethylhexylglycerin is globally approved and as a new substance accords with the European legislation listed on the ELINCS file.International ApprovalsEurope / USA: INCl name: EthylhexylglycerinAustralia: AICS/NICNAS(NA/966),TGACanada:DSLJapan:ENCS as glycerin monoalkyl(or alkenyl,C8-C24)ether(No.: 2-414)CLS 199
Characteristics
0.962
325°C
1.4490 to 1.4530
The oral toxicity of ethylhexylglycerin (Sensiva® SC 50, in polyethylene glycol 400) at doses of 100, 500, and 1,500 mg/kg was evaluated in a 28-day study using groups of 10 rats of an unspecified strain. The test substance was administered at a dose volume of 5 ml/kg.There were no treatment-related mortalities. Body weight development was retarded in mid- and high-dose groups, and this finding was accompanied by a non-statistically significant reduction in food intake when compared to the control (polyethylene glycol 400) group. Both eye and ear functions remained unchanged during the study, and increased salivation (dose not stated) was the only clinical symptom observed. Hematological parameters were unaffected by treatment; however, serum analyses indicated changes in aminotransferase (above normal) in high-dose rats. Urinalysis and necropsy findings were unremarkable.
Characteristic
13.67±0.20(Predicted)
Sealed in dry,Room Temperature
Safety Information
Xi
26-39-61
TY6462200
41-52/53
This glycerol monoalkylether is used as a skin conditioning agent, with bactericidal properties against Gram-positive bacteria.
Ethylhexylglycerin Use and Manufacturing
Ethylhexylglycerin is a natural preservative, used as an alternative to parabens products. It is derived from natural glycerin. Also used as a deodorizer and skin conditioner.Ethylhexylglycerin is a glyceryl ether and serves as an emollient solvent and a fixative with antimicrobial properties, and it is reported to enhance uptake of preservatives in microorganisms. It is often used as an alternative to parabens. The International Nomenclature of Cosmetic Ingredients name is Ethylhexylglycerin, and the chemical formula and synonym names are shown in Figure 1. Ethylhexylglycerin is a colorless to pale viscous liquid. It is reported to be used at a concentration up to 2% in leave-on products and 8% in rinse-off products. It is manufactured and marketed by Schu¨lke & Mayr GMBH, Norderstedt, Germany, under the trade name, Sensiva SC50, which is greater than 99% pure. Ethylhexylglycerin is found in many cosmetic products, that is, antiaging creams, sunscreens, eye shadows, eye creams, lip gloss, deodorants, facial moisturizers, and various types of cleansers.
Ethylhexylglycerin is the novel raw material for deodorants application and is widely used as a cosmetic emollient. Ethylhexylglycerin reliably inhibits the odor-causing bacteria, yeast and fungi on the skin.
Drug Function and Efficacy
Skin conditioning agent, preservative booster, mild antimicrobial properties
Recommended Suppliers of Ethylhexylglycerin
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CN
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IN
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