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Melitracen

Melitracen structure

CAS No:
5118-29-6
Formula:
C21H25N
Chemical Name:
Melitracen
Synonyms:
1-Propanamine,3-(10,10-dimethyl-9(10H)-anthracenylidene)-N,N-dimethyl-;Δ9(10H),γ-Anthracenepropylamine,N,N,10,10-tetramethyl-;3-(10,10-Dimethyl-9(10H)-anthracenylidene)-N,N-dimethyl-1-propanamine;9-(3-Dimethylaminopropylidene)-10,10-dimethyl-9,10-dihydroanthracene;Melitracen;Melitracene;Trausabun;9,10-Dihydro-10,10-dimethyl-9-(3-dimethylaminopropylidene)anthracene;N,N-Dimethyl-3-(10,10-dimethyl-9(10H)-anthrylidene)propylamine;Adaptol;N 7001;Thymeol;U-24973
Categories:
Active Pharmaceutical Ingredients > Nervous System Drugs

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Description

Melitracen is a member of anthracenes.

Melitracen Basic Attributes

Molecular Weight：

291.43

Exact Mass：

291.43

EC Number：

225-858-5

UNII：

Q7T0Y1109Z

DSSTox ID：

DTXSID4048274

ATC Code：

N - Nervous system

HScode：

2921499090

Characteristics

PSA：

3.2

XLogP3：

4.70930

Density：

1.046g/cm3

Boiling Point：

399.1ºC at 760mmHg

Flash Point：

174.4ºC

Refractive Index：

1.4900 (estimate)

Toxicity：

Oral-rat LD50: 170 mg/kg; Oral-Mouse LD50: 315 mg/kg

Flammability characteristics：

Flammable; burning releases toxic nitrogen oxide fumes

Safety Information

Storage features：

Treasury is ventilated, low temperature and dry; stored separately from food materials

Toxicity

Toxicity class：

highly toxic

Drug Information

MeSH：

Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system. (See all compounds classified as Antidepressive Agents, Tricyclic.)

MeSH Entry Terms：

melitracene

Melitracen Use and Manufacturing

Antidepressant.

Computed Properties

Molecular Weight:291.4
XLogP3:5.6
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:291.198699802
Monoisotopic Mass:291.198699802
Topological Polar Surface Area:3.2
Heavy Atom Count:22
Complexity:378
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Bipolar antidepressants, which, at low doses, have stimulant properties

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Flupentixol Melitracen Tablets
Specifications	Each tablet contains flupentixol hydrochloride equivalent to 0.5 mg flupentixol and melitracen hydrochloride equivalent to 10 mg melitracen
Manufacturer	Hainan Huineng Pharmaceutical Co., Ltd.

Delexin Flupentixol Melitracen Tablets
Specifications	Flupentixol 0.5 mg and melitracen 10 mg/tablet

Flupentixol Melitracen Tablets
Ingredients	Flupentixol 0.5 mg and melitracen 10 mg/tablet
Indication	This product can enhance the body's response to ethanol, barbiturates and other central nervous system depressants. Combination with monoamine oxidase inhibitors may cause hypertensive crisis. Neuroleptics and antidepressants can reduce the antihypertensive effect of guanethidine and similar compounds. Antidepressants can also enhance the effects of adrenaline and norepinephrine.
Specifications	Flupentixol 0.5 mg and melitracen 10 mg/tablet

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CAS No.: 5118-29-6

Grade: Industrial Grade

Content: 99%

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