 Home > Encyclopedia > Altrenogest

Altrenogest

Altrenogest structure

CAS No:
850-52-2
Formula:
C21H26O2
Chemical Name:
Altrenogest
Synonyms:
Estra-4,9,11-trien-3-one,17-hydroxy-17-(2-propen-1-yl)-,(17β)-;Estra-4,9,11-trien-3-one,17α-allyl-17-hydroxy-;Estra-4,9,11-trien-3-one,17-hydroxy-17-(2-propenyl)-,(17β)-;(17β)-17-Hydroxy-17-(2-propen-1-yl)estra-4,9,11-trien-3-one;DRC 6246;Allyltrenbolone;R 2267;RU 2267;Altrenogest;Regumate;A 35957;Matrix;Matrix (progestogen)
Categories:
Biochemical Engineering > Inhibitors

Description

Altrenogest(A35957; RU2267) is a progestogen structurally related to veterinary steroid trenbolone.Target: Progesterone ReceptorAltrenogest is a progestogen structurally related to veterinary steroid trenbolone. Treatment of embryo-recipient mares with altrenogest appears to be beneficial in extending the degree of donor-recipient synchrony required for successful embryo transfer. Altrenogest treatment also seems to be conductive to pregnancy maintenance in recipients experiencing luteal

Altrenogest Basic Attributes

Molecular Weight：

310.43

Exact Mass：

310.43

EC Number：

212-703-1

HScode：

2937290090

Characteristics

PSA：

37.3

XLogP3：

4.27560

Appearance：

Slightly yellow powder

Density：

1.1±0.1 g/cm3

Melting Point：

120 °C

Boiling Point：

495.6°C at 760 mmHg

Flash Point：

210.1±21.3 °C

Refractive Index：

1.594

Storage Conditions：

0-6°C

Flammability characteristics：

Flammable; burning produces irritating fumes

Specific rotation：

D20 -72° (c = 0.5 in ethanol)

Safety Information

wgk germany：

RTECS Number：

KG7745000

Storage features：

Treasury is ventilated, low temperature and dry; stored separately from food materials

Altrenogest Use and Manufacturing

Methods of Manufacturing

In a 2L reactor, 500 g of triene (4, 9, 11-triene-3, 17-dione) was added at 10 ° C, use 500 g of ethylene glycol dissolved, And 34 g of HC1 gas was added, The temperature was raised to 60 ° C for 10 h, To the room temperature, the solvent is distilled off. Add 2.5L tetrahydrofuran, cool to below _0 ° C, Slowly drop the newly prepared 187mL allyl magnesium bromide diethyl ether (lmol / L) in the reactor, 3h drop finished, rose to 60 ° C reaction 3h, down to -10 ° C below, 200 mL of water and 200 mL of concentrated hydrochloric acid were added dropwise, Adjust ΡΗ = 1-3, Heating up to 60 ° C, Stirring 5h, Separate the upper, Dried over anhydrous sodium sulfate, The solvent was concentrated to 100 mL, Placed below 5 ° C frozen, Slowly Crystalline Tetraenetrienone crude, ethyl acetate recrystallized about 375g tetraenual estrone. Yield 65percent.In a 21-reactor, At 25 ° (adding 50 (triphenylene) to 4, 9, 11-triene-3, 17-dione) With 50081 ethylene glycol dissolved, And 68 g of HC1 gas was added, The temperature was raised to 60 ° C for 10 h, Down to room temperature, The solvent is distilled off. 4 L of tetrahydrofuran was added, Down to below _0 ° C, Slowly drop the freshly prepared 374 mL allyl magnesium chloride diethyl ether (lmol / L) in a reaction kettle, 3h drops finished, Rose to 50 reactions 2h, Down to below 10 ° C, 200 mL of water and 200 mL of concentrated hydrochloric acid were added dropwise, Adjust ΡΗ = 1-3, Heating up to 60 ° C, Stirring 5h, Separate the upper, Dried over anhydrous sodium sulfate, The solvent was concentrated to 100 mL, Put 5 ° C below the frozen, slow crystallization of tetracene estrone crude, Ethyl acetate was recrystallized to about 347 g tetraenual estrone. Yield 60percent.

Uses

antineoplastic

Recommended Suppliers of Altrenogest

hubei bocare chemical Co.ltd Contact Supplier

CN
1 YR

Business licensed

Trader Supplier of pregabalin,Tirzepatide,Retatrutide,Food Additives,semaglutide,Cosmetics material,Food additive,Chemical intermediate,Active pharmaceutical ingredients

Hot Selling Altrenogest 850-52-2 Factory Supply Raw Materials High Qulity Wholesale price

CAS No.: 850-52-2

Grade: USP / EP / BP / JP Grade

Content: 99.9%

Inquiry
Hangzhou Hyper Chemicals Limited Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

High Quality 98% Veterinary Raw Powder Altrenogest CAS 850-52-2 with ready stock and fast delivery

CAS No.: 850-52-2

Grade: Veterinary Grade

Content: 99%

Inquiry
Xian ZB Biotech Co.,Ltd Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of Herb Extracts,Cosmetic raw materails,API

CAS 850-52-2 99% Purity Female Altrenogest Hormones

CAS No.: 850-52-2

Grade: Pharmaceutical Grade

Content: 99.00%

Inquiry
Shanghai Jinbei Chemical Technology Co., LTD Contact Supplier

CN
2 YRS

Business licensed

Trader Supplier of pharmaceutical，Cosmetic,Pregabalin,2,5-Dimethoxybenzaldehyde,Diphenylacetonitrile,2-Dimethylaminoisopropyl chloride hydrochloride,Tildenafil

Altrenogest CAS 850-52-2 After-sales service Export to many countries Quality assurance

CAS No.: 850-52-2

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Henan Lihao Chem Plant Limited Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of PVC resin,pvc paste resin,melamine

high purity hot sale Altrenogest 99% high quality see COA KANBEI

CAS No.: 850-52-2

Grade: Industrial Grade

Content: 99%

Inquiry