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Home > Encyclopedia > TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2

TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2

TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2 structure

TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2 

structure
  • CAS No:

    80448-90-4

  • Formula:

    C99H155N31O23

  • Chemical Name:

    TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2

  • Synonyms:

    DYNORPHIN A;dynorphin-(1-17);Dynorphin A【pig】;Dynorphin A【rat】;YGGFLRRIRPKLKWDNQ;DYNORPHIN A AMIDE;Dynorphin acetate;DYNORPHIN A (1-17);DYNORPHIN A(HUMAN);DYNORPHIN A PORCINE

  • Categories:

    Biochemical Engineering  >  Polypeptide

Description

Dynorphin is under investigation in clinical trial NCT00000244 (Effects of Dynorphin 1-13 on Heroin Addiction - 1).|A class of opioid peptides including dynorphin A, dynorphin B, and smaller fragments of these peptides. Dynorphins prefer kappa-opioid receptors (RECEPTORS, OPIOID, KAPPA) and have been shown to play a role as central nervous system transmitters.

TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-LYS-LEU-LYS-TRP-ASP-ASN-GLN-NH2 Basic Attributes

2147.51

2146.191162

9M18T0TD14

Characteristics

917.37000

-1.52

1.5±0.1 g/cm3

1.669

−20°C

Safety Information

NONH for all modes of transport

3

22-24/25

Drug Information

Substances used for their pharmacological actions on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function. (See all compounds classified as Neurotransmitter Agents.)

Dynorphin

Computed Properties

Molecular Weight:2147.5
XLogP3:-7.8
Hydrogen Bond Donor Count:33
Hydrogen Bond Acceptor Count:29
Rotatable Bond Count:74
Exact Mass:2147.1945652
Monoisotopic Mass:2146.1912103
Topological Polar Surface Area:917
Heavy Atom Count:153
Complexity:4600
Defined Atom Stereocenter Count:16
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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