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Home > Encyclopedia > O-Desacetyl-N-desmethylDiltiazem

O-Desacetyl-N-desmethylDiltiazem

O-Desacetyl-N-desmethylDiltiazem structure

O-Desacetyl-N-desmethylDiltiazem 

structure
  • CAS No:

    81353-09-5

  • Formula:

    C19H22N2O3S

  • Chemical Name:

    O-Desacetyl-N-desmethylDiltiazem

  • Synonyms:

    1,5-Benzothiazepin-4(5H)-one,2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-,cis-;CHEMBL326233;SCHEMBL5821022;CTK5E8725;AKOS030254430;3-hydroxy-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-2,3-dihydro-1,5-benzothiazepin-4-one;FT-0665915;5-[2-(Methylamino)ethyl]-3-hydroxy-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one

Description

Pale Yellow Solid

O-Desacetyl-N-desmethylDiltiazem Basic Attributes

358.45500

358.13500

Characteristics

87.10000

2.91140

1.239g/cm3

134-136ºC (dec.)

612ºC at 760 mmHg

323.9ºC

1.612

-20ºC Freezer, Under Inert Atmosphere

O-Desacetyl-N-desmethylDiltiazem Use and Manufacturing

A metabolite of Diltiazem (D460620).

Computed Properties

Molecular Weight:358.5
XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:358.13511374
Monoisotopic Mass:358.13511374
Topological Polar Surface Area:87.1
Heavy Atom Count:25
Complexity:442
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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