 Home > Encyclopedia > Toluidine Blue O

Toluidine Blue O

Toluidine Blue O structure

CAS No:
92-31-9
Formula:
C15H16N3S.Cl
Chemical Name:
Toluidine Blue O
Synonyms:
Phenothiazin-5-ium,3-amino-7-(dimethylamino)-2-methyl-,chloride (1:1);Phenothiazin-5-ium,3-amino-7-(dimethylamino)-2-methyl-,chloride;3-Amino-7-(dimethylamino)-2-methylphenothiazin-5-ium chloride;Blutene chloride;Dimethyltoluthionine chloride;Klot;F Klot;Schultz 1041;Tolazul;Tolonium chloride;3-Amino-7-(dimethylamino)-2-methylphenazathionium chloride;Toluidine blue (phenothiazine dye);Toluidine blue;C.I. Basic Blue 17;Toluidine Blue OO;Toluidine Blue O;Gabilin;Menodin;o-Toluidine blue;C.I. 52040;Basic Blue 17;Blutene;NSC 36758;1336-01-2;21785-03-5;24684-06-8;93211-79-1;1335204-66-4;1374634-69-1;2043361-07-3
Categories:
Dyes and Pigments > Dye

Description

green powder

Tolonium chloride is an organic chloride salt having 3-amino-7-(dimethylamino)-2-methylphenothiazin-5-ium (tolonium) as the counterion. It is a blue nuclear counterstain that can be used to demonstrate Nissl substance and is also useful for staining mast cell granules, both in metachromatic and orthochromatic techniques. It has a role as a fluorochrome, a histological dye and a diagnostic agent. It contains a tolonium.|A phenothiazine that has been used as a hemostatic, a biological stain, and a dye for wool and silk. Tolonium chloride has also been used as a diagnostic aid for oral and gastric neoplasms and in the identification of the parathyroid gland in thyroid surgery.

Toluidine Blue O Basic Attributes

Molecular Weight：

305.83

Exact Mass：

305.075348

EC Number：

202-146-2

UNII：

15XUH0X66N

NSC Number：

760421|11225|36758

DSSTox ID：

DTXSID9048728

HScode：

32041300

Characteristics

PSA：

70.39000

XLogP3：

1.27240

Appearance：

Dark green to black Solid

Melting Point：

>200℃

Water Solubility：

H2O: 3.82 g/100 mL

Storage Conditions：

Store at RT.

Toxicity：

Abdominal-rat LD50: 215 mg/kg; intravenous-mouse LD50: 27.56 mg/kg

Flammability characteristics：

Flammable; burning produces toxic nitrogen oxides, sulfur oxides and chloride fumes

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

36/37/38

safety instructions：

22-24/25

RTECS Number：

SP5670000

Storage features：

Warehouse ventilated, low temperature and dry

Stability/Shelf Life：

Stable. Incompatible with strong oxidizing agents.

Precautionary statement(s)：

P264, P270, P301+P312, P330, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 7 companies from 2 notifications to the ECHA C&L Inventory.

Toxicity

Toxicity class：

highly toxic

Drug Information

Drug Indication：

Treatment of dental and oral soft tissue infections

MeSH：

Agents acting to arrest the flow of blood. Absorbable hemostatics arrest bleeding either by the formation of an artificial clot or by providing a mechanical matrix that facilitates clotting when applied directly to the bleeding surface. These agents function more at the capillary level and are not effective at stemming arterial or venous bleeding under any significant intravascular pressure. (See all compounds classified as Hemostatics.)|Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS. (See all compounds classified as Coloring Agents.)|Coagulant substances inhibiting the anticoagulant action of heparin. (See all compounds classified as Heparin Antagonists.)

MeSH Entry Terms：

Blue O, Toluidine

Toluidine Blue O Use and Manufacturing

Uses

Direct dyeing, printing of wool, silk.Biological stain.

Manufacturing Info：

Phenothiazin-5-ium, 3-amino-7-(dimethylamino)-2-methyl-, chloride (1:1): ACTIVE

Use Classification：

Human Drugs -> EU pediatric investigation plans

Computed Properties

Molecular Weight:305.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Exact Mass:305.0753464
Monoisotopic Mass:305.0753464
Topological Polar Surface Area:66.7
Heavy Atom Count:20
Complexity:512
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Recommended Suppliers of Toluidine Blue O

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

Basic Blue 17

CAS No.: 92-31-9

Content: 99.00%

Inquiry
Belami Fine Chemicals Pvt Ltd Contact Supplier

IN
4 YRS

Business licensed Certified factory

Manufactory Supplier of Chemical Reagents,Speciality Cheicals,Stains and indicators,Metal Salts,Fine Chemicals

TOLUIDINE BLUE 92-31-9

CAS No.: 92-31-9

Inquiry