Benzoyl peroxide

white powder or crystals Benzoyl peroxide is an odorless, white or colorless crystalline powder.

1. Cooling conditions in 30% sodium hydroxide solution by adding 30% hydrogen peroxide to generate sodium peroxide solution; and then stirring at 0 ~ 10 ° C dropping benzoyl chloride, the temperature is too high will cause hydrogen peroxide And the product was purified by the method of 2: 1 methanol / chloroform and dried (50-70 ° C) to obtain the product in a yield of 85% or more, and the product was purified by the method described above.
2. In the reactor, add more than 40% of the caustic soda solution, 0.75 parts, diluted with water to about 30%, cooled to 10 ° C under stirring, dropping 30% hydrogen peroxide 1, control reaction temperature (10 ± 2) ° C. After completion of the dropping, the temperature of the material was lowered to about 0 ° C by cooling the brine, and benzoyl chloride was added dropwise while stirring. The reaction temperature was kept below 0 ° C by adjusting the dropping rate of benzoyl chloride and enhancing the heat transfer. After adding benzoyl chloride drop, continue to maintain about 0 ℃, stirring reaction 2 ~ 3h. And then static stratification, release the lower waste, add ice water, while stirring side. And then standing stratification. Separate the lower layer of benzoyl peroxide, low-temperature drying, storage should be retained in the finished product water content of 25% to 30%.
3. 30% of the caustic soda solution will be cooled to 10 ° C stirring, dropping 30% hydrogen peroxide. After the dropwise addition, the temperature of the material was reduced to about 0 ° C, and the benzoyl chloride was added dropwise. Then, the layered product was separated and the lower layer of benzoyl peroxide was separated and dried at a low temperature to maintain a water content of 25% % To save.
4. Benzoyl chloride and hydrogen peroxide and alkali (or sodium peroxide) reaction, cooling, filtration, washing, recrystallization, derived from drying.
5. Ammonium bicarbonate as the basic medium, the other raw materials in the same circumstances, the reaction at room temperature synthesis of BPO's new technology will be a certain amount of benzoyl chloride into the benzoyl chloride tank stand-by; weighing the same quality hydrogen peroxide Stirring, and then adding a small amount of phase transfer catalyst sodium dodecyl sulfate, and then weigh the ammonium carbonate slowly into the reactor. After the ammonium bicarbonate was evenly distributed in the hydrogen peroxide, benzoyl chloride was gradually added dropwise to the reaction kettle at a constant flow rate. The amount of benzoyl chloride was adjusted according to the temperature of the reaction kettle, and kept at about 20 ℃ until benzoyl chloride All cast until the end. The reaction is completed when no gas is released in the reaction vessel. Open the non-blocking pump, the material hit the centrifuge can be dehydrated BPO products.
6. 22g anhydrous Na2CO3 dissolved in 200mL of water, about 15 ℃ in the ice water bath by adding 14mL30% H2O2, 1mL15% activator, and keep the temperature at about 15 ℃ dropping benzoyl chloride 28.0g, after the completion of mechanical Stirring 2h, the reaction generated white granular products, filtration, water once, a white granule product 28.0g. Determination of benzoyl peroxide content over 99% iodine, 22.5% moisture content, yield 90%.
7. Preparation method: In a reaction flask equipped with a stirrer, a thermometer and two dropping funnels, add 100mL (0.29mol) of 10% hydrogen peroxide and cool to about 5 ℃ in an ice water bath. Benzoyl chloride
(1) 28.5 (0.2 mol) and 9.5 g of sodium hydroxide dissolved in 60 mL of water. The dropping speed was controlled to keep the reaction liquid weakly acidic. The reaction of solid precipitation. After stirring, the reaction was continued until no benzoyl chloride odor was observed. Filtration, washing, and then soaked with cold ethanol (to remove the possible presence of benzoic acid and benzoyl chloride), try to drain. Drying after benzoyl peroxide
(1) mp 106-108 ° C, yield 85%.

1. Vitamin B complex
2. Benzoyl Peroxide is a widely used organic compound of the peroxide family. Benzoyl Peroxide is often used in acne treatments , bleaching and polymerizing polyester and many other uses.

Molecular Weight:242.23
XLogP3:3.5
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:242.05790880
Monoisotopic Mass:242.05790880
Topological Polar Surface Area:52.6
Heavy Atom Count:18
Complexity:258
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes