(±)-Brompheniramine maleate
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(±)-Brompheniramine maleate
structure -
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CAS No:
980-71-2
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Formula:
C16H19BrN2.C4H4O4
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Chemical Name:
(±)-Brompheniramine maleate
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Synonyms:
2-Pyridinepropanamine,γ-(4-bromophenyl)-N,N-dimethyl-,(2Z)-2-butenedioate (1:1);Pyridine,2-[p-bromo-α-[2-(dimethylamino)ethyl]benzyl]-,maleate (1:1);2-Pyridinepropanamine,γ-(4-bromophenyl)-N,N-dimethyl-,(Z)-2-butenedioate (1:1);2-[p-Bromo-α-[2-(dimethylamino)ethyl]benzyl]pyridine bimaleate;2-[p-Bromo-α-(2-dimethylaminoethyl)benzyl]pyridine maleate;Brompheniramine maleate;Dimetane maleate;Ilvin maleate;Parabromdylamine maleate;Parabromodylamine maleate;Bromopheniramine maleate;Dimotane;Dimetane;Brompheniramine hydrogen maleate;dl-Bromopheniramine maleate;(±)-Brompheniramine maleate;dl-Brompheniramine maleate;Lodrane;Veltane;Symptom 3;Nagemid;Allent;Ilvin;8055-73-0;32865-01-3
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CAS No:
Description
Brompheniramine maleate is a histamine H1 receptors antagonist.Target: Histamine H1 ReceptorBrompheniramine maleate, is an antihistamine drug of the propylamine (alkylamine) class. It is readily available over the counter and is indicated for the treatment of the symptoms of the common cold and allergic rhinitis. It is a first-generation antihistamine. Brompheniramine has antidepressant properties, inhibiting reuptake of the neurotransmitter serotonin. Based on this knowledge, Arvid Carl
Characteristics
90.73000
3.63950
132-134 °C
403ºC at 760 mmHg
9℃
In water, 2,370 mg/L at 25 deg C (est)
Refrigerator
4.63X10-5 mm Hg at 25 deg C (est)
Oral-rat LD50: 318 mg/kg; Celiac-rat LD50: 76 mg/kg
Thermal decomposition releases toxic nitrogen oxides and bromides, hydrogen chloride fumes
Safety Information
III
6.1(b)
3249
3
22-39/23/24/25-23/24/25-11
36-45-36/37-16-7
US4025000
Xn,Xi,T,F
The warehouse is ventilated, low temperature and dry; stored separately from food raw materials
SENSITIVE TO LIGHT /BROMPHENIIRAMINE MALEATE/
P210-P260-P280-P301 + P310-P311
H225-H301 + H311 + H331-H370
Drug Function and Efficacy
1. Bromhexine hydrochloride can increase the distribution concentration of tetracycline antibiotics in the bronchi. 2. Central nervous system depressants such as sedatives, hypnotics, anticonvulsants and ethanol can increase the effects of acetaminophen, thereby increasing adverse reactions. 3. Acetaminophen can enhance the effects and adverse reactions of anticoagulants. 4. Monoamine oxidase inhibitors can enhance the effects of phenylephrine hydrochloride and increase adverse reactions. Beta-blockers and calcium ion antagonists should not be used to treat hypertension caused by alpha-receptor agonists (phenylephrine hydrochloride in this product). 5. Drug interactions may occur if used simultaneously with other drugs.
Registered Holders
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KESHAVA ORGANICS PVT LTD
Active
India
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SIGMA-ALDRICH IRELAND LIMITED
Active
Ireland
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Benova(Tianjin)Innovation Pharmaceutical Research Co., Ltd.
Active
China
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