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Insulin

Insulin structure

CAS No:
9004-10-8
Chemical Name:
Insulin
Synonyms:
Insulin;Iletin;Endopancrine;Insular;Insulyl;Iszilin;Insulin Injection;Decurvon;HMR 4006;Musulin;Intesulin B;Dermulin;Humilin;LinBit;Afrezza;Humilin R;INS;8049-95-4;8049-67-0;9004-12-0;9037-76-7;9045-66-3;9045-65-2;9045-63-0;9045-67-4;9066-40-4;9066-39-1;11081-38-2;37243-75-7;37294-43-2;57126-42-8;69090-47-7;88026-12-4;88026-11-3;11097-08-8
Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Description

ChEBI: A peptide hormone produced in the pancreas and involved in regulating the metabolism of carbohydrates (particularly glucose) and fats. Commonly thought of as a protein, it consists of two petide chains, one containing 21 amino acid residues and the other c ntaining 30; the chains are joined together by 2 disulfide bonds. Recombinant insulin is identical to human insulin, but is synthesised by inserting the human insulin gene into E. coli, which then produces insulin for human use. It is

Insulin Basic Attributes

Molecular Weight：

5777.59

Exact Mass：

5791.629

EC Number：

235-703-3

Characteristics

PSA：

2450

XLogP3：

-12.8

Appearance：

solution

Density：

1.09 g/cm³

Melting Point：

233 °C

Water Solubility：

acidified water, pH 2.0: 2 mg/mL

Storage Conditions：

2-8°C

PH：

2.5-3.5

Safety Information

wgk germany：

safety instructions：

22-24/25

RTECS Number：

NM8900250

Stability/Shelf Life：

EXPIRATION OF NOT LATER THAN 24 MO; DISCOLORATION, TURBIDITY, OR VISCOSITY INDICATES DETERIORATION OR CONTAMINATION

Insulin Use and Manufacturing

Used for the treatment of middle and severe diabetes, malnutrition, cirrhosis and other diseases

Computed Properties

Molecular Weight:5794
XLogP3:-12.8
Hydrogen Bond Donor Count:78
Hydrogen Bond Acceptor Count:89
Rotatable Bond Count:178
Exact Mass:5791.6287098
Monoisotopic Mass:5789.6220002
Topological Polar Surface Area:2450
Heavy Atom Count:404
Complexity:14600
Defined Atom Stereocenter Count:52
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Homeopathic form of insulin used for glucose metabolism and carbohydrate regulation

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

HEALTHY WEIGHT FORMULA- asclepias vincetoxicum, echinachea, hypothalamus, brain, hepar suis, methylcobalamin, pancreas suis, renal, stomach(suis), aacg-a, aacg-b, calcarea carbonica, gambogia, gelsemium sempervirens, graphites, nux vomica, phytolacca decandra, 7-keto dhea, atp, glucagon, insulin, sarcolacticum acidum, proteus bach_liquid
Manufacturer	Healing Power Within Inc.

Registered Holders

Wuhan Biochemical Pharmaceutical Co., Ltd.

China
Active
Xuzhou Wanbang Jinqiao Pharma Co., Ltd.

China
Active
Nanjing Xinbai Pharmaceutical Co., Ltd.

China
Active