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insulin glargine

pharmaceutical raw materials
insulin glargine structure

insulin glargine 

structure
  • CAS No:

    160337-95-1

  • Formula:

    C267H404N72O78S6

  • Chemical Name:

    insulin glargine

  • Synonyms:

    insulin glargine;A21-Gly-B31-Arg-B32-Arg-insulin;Insulin, glycyl(A21)-arginyl(B31,B32)-;Lantus;Solostar;Solostar [insulin delivery pen];Unii-2zm8cx04rz;Insulin Glargine EP/USP

  • Categories:

    Active Pharmaceutical Ingredients  >  Hormones and the Endocrine System

insulin glargine Basic Attributes

6062.955

6060.825

2937120000

Characteristics

2590

-14.1

81

Safety Information

P260, P314, P501

H373

insulin glargine Use and Manufacturing

long-acting basal insulin analogue, helping control the blood sugar level of those with type 1 and type 2 diabetes mellitus. It is an analogue of human insulin made by replacing the asparagine residue at position A21 of the A-chain with glycine and adding

Drug Function and Efficacy

Antidiabetic drugs. Long-acting insulin and its analogs. Glargine insulin is a human insulin analog with low solubility in neutral pH liquid. It forms fine deposits and is continuously released after subcutaneous injection, producing a stable, non-peak blood drug concentration/time characteristic. Its main function is to regulate sugar metabolism, lowering blood sugar by promoting the uptake of glucose by peripheral tissues such as skeletal muscle and fat and inhibiting the production of glucose in the liver, while inhibiting lipolysis in fat cells, inhibiting proteolysis and promoting protein synthesis.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Registered Holders

  • Sanofi (China) Investment Co., Ltd.

    China China
    Active
  • Liaoning Boao Biological Pharmaceutical Co., Ltd.

    China China
    Active
  • Tonghua Dongbao Pharmaceutical Co., Ltd.

    China China
    Active

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