insulin glargine
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insulin glargine
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CAS No:
160337-95-1
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Formula:
C267H404N72O78S6
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Chemical Name:
insulin glargine
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Synonyms:
insulin glargine;A21-Gly-B31-Arg-B32-Arg-insulin;Insulin, glycyl(A21)-arginyl(B31,B32)-;Lantus;Solostar;Solostar [insulin delivery pen];Unii-2zm8cx04rz;Insulin Glargine EP/USP
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Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System
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CAS No:
insulin glargine Use and Manufacturing
long-acting basal insulin analogue, helping control the blood sugar level of those with type 1 and type 2 diabetes mellitus. It is an analogue of human insulin made by replacing the asparagine residue at position A21 of the A-chain with glycine and adding
Drug Function and Efficacy
Antidiabetic drugs. Long-acting insulin and its analogs. Glargine insulin is a human insulin analog with low solubility in neutral pH liquid. It forms fine deposits and is continuously released after subcutaneous injection, producing a stable, non-peak blood drug concentration/time characteristic. Its main function is to regulate sugar metabolism, lowering blood sugar by promoting the uptake of glucose by peripheral tissues such as skeletal muscle and fat and inhibiting the production of glucose in the liver, while inhibiting lipolysis in fat cells, inhibiting proteolysis and promoting protein synthesis.
Registered Holders
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Sanofi (China) Investment Co., Ltd.
Active
China
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Liaoning Boao Biological Pharmaceutical Co., Ltd.
Active
China
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Tonghua Dongbao Pharmaceutical Co., Ltd.
Active
China
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