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Insulin degludec

pharmaceutical raw materials
Insulin degludec structure

Insulin degludec 

structure
  • CAS No:

    844439-96-9

  • Formula:

    C274H411N65O81S6

  • Chemical Name:

    Insulin degludec

  • Synonyms:

    (1A-21A),(1B-29B)-insulin (human), 29B-(N6-(N-(15-carboxy-1- oxopentadecyl)-L-gamma- glutamyl)-L-lysine)-;degludec;insulin degludec;UNII-54Q18076QB;54Q18076QB;Tresiba;Insulin degludec [USAN:INN];NN 1250

  • Categories:

    Active Pharmaceutical Ingredients  >  Hormones and the Endocrine System

Insulin degludec Basic Attributes

6104.036

6101.843

Characteristics

2510

-4.9

Computed Properties

Molecular Weight:6104
XLogP3:-4.9
Hydrogen Bond Donor Count:79
Hydrogen Bond Acceptor Count:92
Rotatable Bond Count:197
Exact Mass:6101.8431193
Monoisotopic Mass:6099.8364096
Topological Polar Surface Area:2510
Heavy Atom Count:426
Complexity:15300
Defined Atom Stereocenter Count:51
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

It specifically binds to human insulin receptors and produces the same pharmacodynamic effects as human insulin. It promotes glucose uptake by binding to receptors on muscle and fat cells, while inhibiting the liver's output of glucose, thereby exerting a blood sugar-lowering effect.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Registered Holders

  • Novo Nordisk (China) Pharmaceuticals Co., Ltd.

    China China
    Active
  • CHONGQING CHEN'AN BIOPHARMACEUTICAL CO LTD

    United States United States
    Active
  • YIFAN PHARMACEUTICAL (SHANGHAI) CO LTD

    United States United States
    Active

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