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Neomycin C

Neomycin C structure

Neomycin C 

structure
  • CAS No:

    66-86-4

  • Formula:

    C23H46N6O13

  • Chemical Name:

    Neomycin C

  • Synonyms:

    D-Streptamine,O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-;Neomycin C;D-Streptamine,O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)-O-[O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→3)-β-D-ribofuranosyl-(1→5)]-2-deoxy-;O-2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine;Dekamycin II;24717-75-7

  • Categories:

    Biochemical Engineering  >  Saccharides

Description

ChEBI: A tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine C.


Neomycin C is a tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine C. It is a conjugate base of a neomycin C(6+).|Neomycin C is one of the two major active isomeric components of the neomycin complex. Neomycin C is approximately half as active as neomycin B.

Neomycin C Basic Attributes

614.65

614.64

215-766-3

6B1U1NS16Z

C95127

Characteristics

353

-9

1.3548 (rough estimate)

Soluble in water ... solutions up to 250 mg/mL may be prepared

1.60X10-28 mm Hg at 25 °C (est)

Safety Information

Hygroscopic. /Neomycin sulfate/

Drug Information

neomycin C

Neomycin C Use and Manufacturing

Neomycin C, is an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia.

Computed Properties

Molecular Weight:614.6
XLogP3:-9
Hydrogen Bond Donor Count:13
Hydrogen Bond Acceptor Count:19
Rotatable Bond Count:9
Exact Mass:614.31228554
Monoisotopic Mass:614.31228554
Topological Polar Surface Area:353
Heavy Atom Count:42
Complexity:872
Defined Atom Stereocenter Count:19
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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