5-BROMO-6-PHENYL-3(2H)-PYRIDAZINONE

To a solution of 3, 4-dibromo-5-phenylfuran-2(5H)-one (600 mg, 1.887 mmol) in 5 mL EtOH at 0°C was added hydrazine hydrate (0.102 ml, 2.076 mmol). The reaction mixture was stirred at room temperature for 10 mins before heating under reflux for 2 h. The reaction mixture was allowed to cool to room temperature and a precipitate formed. The precipitate was collected by filtration and washed with cold ethanol to provide 5-Bromo-6-phenylpyridazin-3(2H)-one (16, 458mg , 99percent yield) as a pale orange solid. LCMS m/z = 251 [M+H]+

Molecular Weight:251.08
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:249.97418
Monoisotopic Mass:249.97418
Topological Polar Surface Area:41.5
Heavy Atom Count:14
Complexity:303
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes