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Carmine

Carmine structure

CAS No:
1390-65-4
Chemical Name:
Carmine
Synonyms:
Carmine;B Rose Liquid;Carmine red;CC 1000WS;8022-93-3;52011-97-9
Categories:
Cosmetic Ingredient > Cosmetic Colorant

Description

Coloring matter from the insect Coccus cacti L. It is used in foods, pharmaceuticals, toiletries, etc., as a dye, and also has use as a microscopic stain and biological marker.

Carmine Basic Attributes

Molecular Weight：

492.39

Exact Mass：

492.090393

EC Number：

215-023-3

Characteristics

PSA：

256.66000

XLogP3：

4.80

Appearance：

red powder

Density：

1.9±0.1 g/cm3

Melting Point：

298-300 °C (decomp)

Boiling Point：

907.6±65.0 °C at 760 mmHg

Flash Point：

316.1±27.8 °C

Refractive Index：

1.792

Water Solubility：

ammonium hydroxide: soluble1mg/mL

Storage Conditions：

Store at +5°C to +30°C.

Vapor Pressure：

5.07X10-27 mm Hg at 25 °C (est)

Specific rotation：

Specific optical rotation (water): +51.6 deg at 15 °C/654 angstroms

PH：

pH = 4.8 (yellow); pH = 6.2 (violet)

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

safety instructions：

22-24/25

RTECS Number：

FH8891000

Stability/Shelf Life：

Stable. Incompatible with strong oxidizing agents.

Drug Information

MeSH：

Natural or synthetic dyes used as coloring agents in processed foods. (See all compounds classified as Food Coloring Agents.)|Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS. (See all compounds classified as Coloring Agents.)

MeSH Entry Terms：

7-glucopyranosyl-3,5,6,8-tetrahydroxyl-1-methyl-9,10-dioxoanthracene-2-carboxylic acid

Carmine Use and Manufacturing

Methods of Manufacturing

A concentrated solution obtained by extracting cochineal females with water, dilute ethanol or methanol, and then removing ethanol or methanol.

Uses

Preparation of carminic acid, overall staining in embryology, staining of nuclei, titration of ammonia solution indicator, microscopic analysis, fluorescence analysis, dyeing, coloring of food, etc. It can be used to calibrate and standardize the detection method of synthetic pigments in food, and can also be used as a working standard for daily analysis and detection.

Use Classification：

Cosmetics -> Cosmetic colorant

Computed Properties

Molecular Weight:492.4
XLogP3:0.5
Hydrogen Bond Donor Count:9
Hydrogen Bond Acceptor Count:13
Rotatable Bond Count:3
Exact Mass:492.09039069
Monoisotopic Mass:492.09039069
Topological Polar Surface Area:243
Heavy Atom Count:35
Complexity:864
Defined Atom Stereocenter Count:5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Natural red pigment derived from cochineal insects; used for pink to red shades

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

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